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1 July 2019 | By Vanda Dolabela de Magalhães
Purification of a drug from host cell protein contaminants can be challenging, with low-level contamination often remaining after purification. Vanda Dolabela de Magalhães shares discussions on the subject from six Brazilian companies working in the biotech field.
1 July 2019 | By Ioannis A. Papayannopoulos, Shannon Renn-Bingham
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
25 June 2019 | By Waters
Introduced at ASMS 2019, the new SYNAPT XS provides ultimate flexibility offering greater freedom of analytical choice to support scientific creativity and technical success for any application.
11 June 2019 | By ionBench
Overview on how ionBench products can help LC/MS users with dedicated furniture for their instrumentation
10 June 2019 | By Sciex
Building from the company’s best-selling SCIEX Triple Quad™ for over 10 years, users can now get triple quad sensitivity plus QTRAP® functionality in one system.
3 June 2019 | By Thermo Fisher Scientific
Thermo Scientific Orbitrap Exploris 480 mass spectrometer designed for high-throughput biopharmaceutical and academic research laboratories.
30 May 2019 | By European Pharmaceutical Review
Researchers succeed in using machine learning to make the mass analysis of proteins faster and almost error-free.
25 March 2019 | By JEOL
JEOL introduces new GC/triple quadrupole mass spectrometer with high speed and high sensitivity for trace detection of pesticides, dioxins and regulated chemicals.
8 March 2019 | By Nikki Withers (European Pharmaceutical Review)
The goal is to improve manufacturing flexibility, enhance quality and uniformity, while lowering the costs for patients...
26 February 2019 | By European Pharmaceutical Review
In this issue: identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS, and open data policies in proteomics.
26 February 2019 | By Ahmad Amini, Henrik Lodén, Torgny Rundlöf
Matrix-assisted laser desorption/ionisation (MALDI) time-of-flight (TOF) mass spectrometry (MS) has proven to be an excellent technique for identification of illegally distributed peptides and proteins for human use. The identification of proteins is mainly based on peptide mass fingerprinting (PMF) – ie, the bottom-up approach – while the small proteins and…
19 February 2019 | By Sciex
Antibody-drug conjugates (ADC’s) are targeted cancer therapeutics that deliver a cytotoxic agent, the payload, to the tumour.
5 February 2019 | By Sciex
Amlodipine is an angioselective calcium channel blocker used to treat high blood pressure, chest pain and other conditions caused by coronary artery disease.
18 January 2019 | By Sciex
Multi-component methods for the detection of different compound classes, such as vitamins and amino acids, have been established and are widely used to analyse a broad range of samples.
11 January 2019 | By Nikki Withers (European Pharmaceutical Review)
Study using mass spectrometry-based analysis provides a greater understanding of the cell and a comprehensive map of cell proteins...
