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25 March 2019 | By JEOL
JEOL introduces new GC/triple quadrupole mass spectrometer with high speed and high sensitivity for trace detection of pesticides, dioxins and regulated chemicals.
8 March 2019 | By Nikki Withers (European Pharmaceutical Review)
The goal is to improve manufacturing flexibility, enhance quality and uniformity, while lowering the costs for patients...
26 February 2019 | By European Pharmaceutical Review
In this issue: identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS, and open data policies in proteomics.
26 February 2019 | By Ahmad Amini, Henrik Lodén, Torgny Rundlöf
Matrix-assisted laser desorption/ionisation (MALDI) time-of-flight (TOF) mass spectrometry (MS) has proven to be an excellent technique for identification of illegally distributed peptides and proteins for human use. The identification of proteins is mainly based on peptide mass fingerprinting (PMF) – ie, the bottom-up approach – while the small proteins and…
19 February 2019 | By Sciex
Antibody-drug conjugates (ADC’s) are targeted cancer therapeutics that deliver a cytotoxic agent, the payload, to the tumour.
5 February 2019 | By Sciex
Amlodipine is an angioselective calcium channel blocker used to treat high blood pressure, chest pain and other conditions caused by coronary artery disease.
18 January 2019 | By Sciex
Multi-component methods for the detection of different compound classes, such as vitamins and amino acids, have been established and are widely used to analyse a broad range of samples.
11 January 2019 | By Nikki Withers (European Pharmaceutical Review)
Study using mass spectrometry-based analysis provides a greater understanding of the cell and a comprehensive map of cell proteins...
8 January 2019 | By Sciex
A complete workflow to quantify intact therapeutic proteins in plasma matrix has been developed, covering three critical components in preclinical sample analysis: target protein enrichment/purification, LC/MS data acquisition and quantitative data analysis.
19 December 2018 | By European Pharmaceutical Review
Keeping up with the latest developments in pharma.
13 December 2018 | By Merck Millipore
SOLu-Trypsin is an Advanced Proteomics Grade enzyme that is solution stable for mass spectrometry.
13 December 2018 | By Merck Millipore
Instrument agnostic consumables available for an HPLC or LC-MS workflow lab.
12 December 2018 | By PharmaFluidics
The use of micro pillar array columns (μPAC™) for characterising antibody-drug conjugates is presented. Kadcyla® (ado-trastuzumab emtansine) and, for comparison, Herceptin® (trastuzumab) tryptic digests were analysed on a 200 cm μPAC™ C18 column and peaks eluting were detected by ultraviolet (UV) spectroscopy and high-resolution mass spectrometry (MS).
12 December 2018 | By MilliporeSigma
HPLC is a rapid, accurate and sensitive method for determination of pharmaceutical drugs, degradations and impurity profiling. It is a preferred method for analytical characterisation during drug development.
15 October 2018 | By European Pharmaceutical Review
The Dynamic Mass Spectrometry Probe uses microfluidic technology to help separate compounds of interest from the salts in less than a minute...
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