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This whitepaper reports on the use of μPAC™ in combination with MS for the characterisation of HCPs and their monitoring during downstream processing.
Characterisation and quality control of proteinbased biotherapeutics has historically been a lengthy and challenging process due to their complexity and inherent heterogeneity.
The FDA has issued a statement on the results from ranitidine medication testing for nitrosamines, saying that they contain no more NDMA than smoked meats.
Research has found that the worldwide LC-MS market will be worth $2750 million by the end of the forecast period in 2024.
Dr Carsten Hopf and his team are using MALDI imaging in several applications, including drug metabolite and formulation distributions in tissues. This article investigates how this content-rich technique is enabling researchers to gain unique insights to facilitate faster and better drug discovery.
Purification of a drug from host cell protein contaminants can be challenging, with low-level contamination often remaining after purification. Vanda Dolabela de Magalhães shares discussions on the subject from six Brazilian companies working in the biotech field.
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
Introduced at ASMS 2019, the new SYNAPT XS provides ultimate flexibility offering greater freedom of analytical choice to support scientific creativity and technical success for any application.
Overview on how ionBench products can help LC/MS users with dedicated furniture for their instrumentation
Building from the company’s best-selling SCIEX Triple Quad™ for over 10 years, users can now get triple quad sensitivity plus QTRAP® functionality in one system.
Thermo Scientific Orbitrap Exploris 480 mass spectrometer designed for high-throughput biopharmaceutical and academic research laboratories.
Researchers succeed in using machine learning to make the mass analysis of proteins faster and almost error-free.
JEOL introduces new GC/triple quadrupole mass spectrometer with high speed and high sensitivity for trace detection of pesticides, dioxins and regulated chemicals.
The goal is to improve manufacturing flexibility, enhance quality and uniformity, while lowering the costs for patients...
In this issue: identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS, and open data policies in proteomics.
