news
Global LC-MS market to exhibit CAGR of 6.9 percent
Research has found that the worldwide LC-MS market will be worth $2750 million by the end of the forecast period in 2024.
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article
Advanced MALDI imaging breaks ground in pharmaceutical research
Dr Carsten Hopf and his team are using MALDI imaging in several applications, including drug metabolite and formulation distributions in tissues. This article investigates how this content-rich technique is enabling researchers to gain unique insights to facilitate faster and better drug discovery.
article
Assessing host cell protein contamination in biotechnological products
Purification of a drug from host cell protein contaminants can be challenging, with low-level contamination often remaining after purification. Vanda Dolabela de Magalhães shares discussions on the subject from six Brazilian companies working in the biotech field.
article
Analytical methods used in obtaining higher order structure information from protein therapeutics
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
product
Video: Introducing the new SYNAPT XS High Resolution Mass Spectrometer
Introduced at ASMS 2019, the new SYNAPT XS provides ultimate flexibility offering greater freedom of analytical choice to support scientific creativity and technical success for any application.
product
IonBench: Manufacturer of mobile benches for mass spectrometry and liquid chromatography
Overview on how ionBench products can help LC/MS users with dedicated furniture for their instrumentation
news
SCIEX Triple Quad™ 5500+ LC-MS/MS system – QTRAP® ready launches at ASMS 2019
Building from the company’s best-selling SCIEX Triple Quad™ for over 10 years, users can now get triple quad sensitivity plus QTRAP® functionality in one system.
news
New-generation benchtop mass spectrometer advances quantitative proteomics and translational research
Thermo Scientific Orbitrap Exploris 480 mass spectrometer designed for high-throughput biopharmaceutical and academic research laboratories.
news
Proteomics research advanced by use of AI
Researchers succeed in using machine learning to make the mass analysis of proteins faster and almost error-free.
news
New JEOL GC/triple quadrupole mass spectrometer introduced at Pittcon
JEOL introduces new GC/triple quadrupole mass spectrometer with high speed and high sensitivity for trace detection of pesticides, dioxins and regulated chemicals.
news
Continuous manufacturing method used to make generic lomustine
The goal is to improve manufacturing flexibility, enhance quality and uniformity, while lowering the costs for patients...
article
Mass Spectrometry In-Depth Focus 2019
In this issue: identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS, and open data policies in proteomics.
article
Identification of peptides and proteins in suspected illegal medicinal products using MALDI-TOF-MS
Matrix-assisted laser desorption/ionisation (MALDI) time-of-flight (TOF) mass spectrometry (MS) has proven to be an excellent technique for identification of illegally distributed peptides and proteins for human use. The identification of proteins is mainly based on peptide mass fingerprinting (PMF) – ie, the bottom-up approach – while the small proteins and…
Whitepapers/App Notes/Posters
Application Note: Sensitive quantitation of the ADC ado-trastuzumab emtansine free cytotoxic drug DM1 in serum using MicroLC-MS
Antibody-drug conjugates (ADC’s) are targeted cancer therapeutics that deliver a cytotoxic agent, the payload, to the tumour.
Whitepapers/App Notes/Posters
Application Note: Highly selective bioanalytical quantitation method for analysis of R and S amlodipine enantiomers in human plasma using LC-MS/MS
Amlodipine is an angioselective calcium channel blocker used to treat high blood pressure, chest pain and other conditions caused by coronary artery disease.