Whitepapers/App Notes/Posters

Application note: Cleaning validation from HPLC to TOC: three factors to consider

Posted: 25 April 2019 | | No comments yet

This application note from SUEZ outlines the factors that companies should consider when choosing their cleaning validation procedure, highlighting the benefits of TOC analysis over HPLC.

Total Organic Carbon (TOC) analysis is often preferred over traditional, product-specific methods for cleaning validation due to its speed, simplicity, and ability to enhance process understanding.

HPLC vs. TOC

TOC analysis offers several benefits over HPLC, including:

• Better process understanding
• Faster sample analysis
• Simpler method development

• Greater productivity
• Opportunity for at-line and online efficiency gains
• Lower operating costs.











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This content is provided to you for free thanks to the kind support of our sponsors: SUEZ

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