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HPLC - Articles and news items

Whitepaper: Facilitating filtration of small volumes

Facilitating filtration of small volumes: HPLC and UHPLC sample prep

Whitepapers / 21 July 2016 / Pall Laboratory

Filtrating small volumes of fluid (< 2 mL) can be difficult due to the volume remaining inside the filter after use, so Pall Laboratory have developed 13 mm syringe filters with mini spike outlets for filtration of small volume samples...

How to avoid residual solvent when drying reverse phase HPLC fractions and prevent the formation of gums and oils.

How to avoid residual solvent when drying reverse phase HPLC fractions and prevent the formation of gums and oils.

Supplier news / 26 February 2016 / Biopharma Group

Traditional concentration of reverse phase HPLC fractions to dryness in a Genevac HT evaporator is a fast and safe process…

Easy and Quick HPLC Analysis of Aflatoxin in Milk

Easy and quick HPLC analysis of Aflatoxin in milk

Supplier news / 15 February 2016 / YMC Europe GmbH

Aflatoxins are naturally occurring mycotoxins that are produced by different species of fungi…

CHIRAL ART polysaccharide HPLC columns by YMC now with 3 µm!

CHIRAL ART polysaccharide HPLC columns by YMC now with 3 µm!

Supplier news / 3 February 2016 / YMC Europe

To overcome the need of method developers for faster and high-resolution methods, YMC now offers all of its CHIRAL ART polysaccharide HPLC columns with a particle size of 3 µm…

HPLC Congress 2016- Exploring the Boundless Analytical Techniques

HPLC Congress 2016- Exploring the boundless analytical techniques

Supplier news / 16 September 2015 / HPLC

Microanalysis which is critical in today’s research is ushered by boundless analytical techniques, the major one being HPLC…

Thermo Fisher Scientific

Thermo Fisher Scientific Receives IVDD CE Mark for its Thermo Scientific Prelude MD HPLC, Endura MD Mass Spectrometer and ClinQuan MD Software

Supplier news / 10 September 2015 / Thermo Fisher Scientific

Now available to clinical laboratories in Europe for general in vitro diagnostic use …

Wanted: clever minds!

Wanted: clever minds!

Supplier news / 10 September 2015 / Shimadzu

‘lab4you’ program for young scientists / Laboratory space available for research / Brief abstract for application…

Webinar Feature Image

Increasing Throughput and Sensitivity of LC-MS assays with a focus on MS optimisation and novel LC strategies

Webinars / 13 July 2015 / Sciex

Simplifying peptide quantification with automated optimisation of MRM transitions and advantages of Micro flow LC to maximise LC-MS performance…

Universal detection in high performance liquid chromatography

Universal detection in high performance liquid chromatography

Chromatography, Issue 3 2015 / 3 July 2015 / David P. Elder, Phil Borman and George Okafo - GlaxoSmithKline

The most commonly used analytical technique for the testing of drug molecules is reversed-phase high performance liquid chromatography (RP-HPLC) with ultraviolet (UV)/visible detection. However, one of the biggest constraints affecting UV/visible detectors is their inability to generate adequate sensitivity for analytes lacking a suitable UV chromophore. These compounds comprise a surprisingly large group, encompassing natural products, particularly fermentation products, carbohydrates, lipids, certain amino acids, steroids, bisphosphonates, alkylating agents, excipients, polymer, surfactants, etc. (see Figure 1, page 50, for some representative structures). Secondly, it is often assumed that response factors for impurities are the same as for the parent when using UV detection systems, when often they are not. Accordingly, purity assessments are inevitably compromised to some degree. This short review will look at the use of some newer detection systems and the pros and cons of the various detector types. Hyphenated techniques such as HPLC-NMR and HPLC-MS have been deliberately excluded…

LC-MS Supplement

LC-MS: In-depth focus 2015

Chromatography, Issue 2 2015, Supplements / 20 April 2015 / David Elder, Phil Borman, George Okafo, William McDowell, Hanne Røberg-Larsen

In this free-to-view LC-MS in-depth focus, we delve into the world of glycans, and how their natural complexity necessitates sophisticated sequencing techniques, while another article aims to demonstrate the versatility of LC-MS and the ease with which it can be combined with a variety of MS systems, focusing particularly on nanoLC…

HPLC: On-chip liquid chromatographic separation

HPLC: On-chip liquid chromatographic separation

Chromatography / 17 April 2015 / Makoto Tsunoda, University of Tokyo

High-performance liquid chromatography (HPLC) is a powerful separation technique due to its high accuracy, precision, versatility and robustness. In the development of pharmaceuticals, it is no doubt that LC is a key technology in the quality control of pharmaceuticals and pharmacokinetic studies and in the analysis of complex biological compounds in bio-samples for the clarification of the function of biological systems. Nowadays, pharmaceutical developments require that HPLC analyses are fast and efficient. However, reducing separation times in LC without reducing the separation efficiency requires generating higher resolving power per unit time while speeding separation times without lessening the quality of the separation enables important analytical information to be generated more quickly. To achieve these goals in LC, monolithic column, high-temperature LC, fused-core column and ultra high-pressure LC with sub-2µm particles packed into column have been developed. This review will focus on chip-based pressure-driven LC separation…

Thermo-CD

Thermo Fisher Scientific adds new Atlas CDS software control for Shimadzu Prominence HPLC

News, Supplier news / 21 March 2011 / The Scott Partnership

Now available…Thermo Scientific Atlas CDS instrument control software…

 

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