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Merck Millipore - Articles and news items
Whitepapers / 15 January 2016 / Merck Millipore
The Milliflex® Quantum system (Merck Millipore) is a rapid method for the quantitative detection of contaminants in filterable samples…
Merck appoints Udit Batra to head combined life science business ahead of planned Sigma-Aldrich acquisition
Industry news / 14 April 2015 / Victoria White
Merck has announced that Udit Batra has been appointed to lead the combined life science business of Merck Millipore and Sigma-Aldrich…
Merck Millipore congratulates winner of the Alice C. Evans Award for Leadership in Clinical Microbiology
Supplier news / 20 May 2014 / Merck
Merck Millipore announced that Bonnie Bassler, Ph.D., Squibb Professor and Chair of the Department of Molecular Biology, Princeton University, has won the 2014 Merck Millipore Alice C. Evans Award for Leadership in Clinical Microbiology…
Revisiting a mutual recognition agreement approach for GMP inspections to secure the safety of the supply chain of APIs.
Solid form diversity of commonly used tableting excipients and its impact.
The chemical safety assessment process for extractables and leachables associated with packaged pharmaceutical products.
INTERPHEX 2013: Show preview
Merck Millipore, announced that the division was invited to serve on the faculty of the CPIER at Peking University…
Merck Millipore has completed the acquisition of the microbiology business of Biotest AG…
Whitepaper: The importance of being profiled: Improving drug candidate safety and efficacy using cross-target profiling
Whitepapers / 11 July 2011 / Merck Millipore
Profiling of putative lead compounds against a representative panel of important enzymes, receptors, ion channels and transporters is an excellent way to establish a preliminary view of potential issues that might later hamper development. An early idea of which off-target activities must be minimized can save valuable time and money during the preclinical lead optimization phase if pivotal questions are asked beyond the usual profiling at hERG. The best data for critical evaluation of activity at GPCRs and ion channels is obtained using functional assays, since binding assays cannot detect all interactions and do not provide information on whether the interaction is that of an agonist, antagonist, or allosteric modulator. This overview discusses the benefits of in vitro assays, specific decision points where profiling can be of immediate benefit, and highlights relevant profiling services offered by Merck Millipore.
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