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Application note: Representative sampling in process Raman spectroscopy

Posted: 13 December 2017 | | No comments yet

Raman spectroscopy is an analysis technique that provides a “molecular fingerprint” of the sample, enabling analysis of chemical composition and molecular structure without sample preparation..

As a measurement technique, Raman imparts many benefits in applications from laboratory discoveries to feedback-control in manufacturing.

In situ real-time analysis, compatibility with aqueous systems, non-destructive nature, and high chemical specificity means that the Raman-analysed sample is representative of the process. Because Raman is a non-destructive technique, the same sample measured by Raman can also be measured by other analytical techniques.

These well-known features have been harnessed throughout the pharmaceutical industry for small molecule pharmaceutical manufacturing and bioprocessing.

 

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