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1 July 2019 | By Zafar Iqbal
Zafar Iqbal sheds light on how Raman spectroscopy is used to detect and understand the amorphous phase in a range of solids, providing examples of his own laboratory applications.
1 July 2019 | By Ioannis A. Papayannopoulos, Shannon Renn-Bingham
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
28 June 2019 | By Dr Chiraz Frydman - Global Senior Product Manager at HORIBA France
Many researchers are keen to find analytical solutions that generate the chemical fingerprint of a sample at the molecular and cellular level. Overcoming these problems is made possible by label-free techniques such as Raman, SPRi or particle size analysis. This brief overview will identify the benefits of Raman spectroscopy.
27 June 2019 | By Harald Fischer
High-resolution measurements of particles are of great interest in many fields of application. Combining confocal Raman microscopy with particle analysis tools makes it possible to find, classify and identify particles almost entirely automatically.
25 June 2019 | By European Pharmaceutical Review
Analytical techniques for QA/QC purposes are integral to the safe production of therapeutics. This in-depth focus looks at Raman spectroscopy for amorphous phase analysis and discusses the viable but non-culturable (VBNC) state of bacteria in environmental monitoring.
24 January 2019 | By Resolution Spectra Systems
ProCellics™ software is available with ProCellics™ GMP bioprocess in-line analyser. ProCellics™ software has been specifically developed to address bioprocess monitoring needs...
3 January 2019 | By Anik Alam, Derya Cebeci, Dor Ben-Amotz
There has been a lot of interest in enhancing the sensitivity of Raman spectroscopy due to the low efficiency of the Raman technique. A pre-concentration technique, drop-coating deposition Raman (DCDR), has been used in recent years to increase the utility of Raman spectroscopy by decreasing the detection limit for non-enhanced…
2 January 2019 | By Charlotte De Bleye (University of Liege Belgium), Elodie Dumont (University of Liege Belgium), Eric Ziemons (University of Liege Belgium), Hermane Avohou (University of Liege Belgium), Laureen Coic (University of Liege Belgium), Philippe Hubert (University of Liege Belgium), Pierre-Yves Sacre (University of Liege Belgium), Riccardo Deidda (University of Liege Belgium), Roland Marini (University of Liege Belgium)
Quality medicines are essential to any healthcare system and are the final goal of any pharmaceutical manufacturer. Unfortunately, as stated recently by the World Health Organization (WHO), one in 10 medical products circulating in low and middle-income countries is either substandard or falsified (SF products).1 Although the exact prevalence of…
19 December 2018 | By Kaiser Optical Systems
The FDA’s Quality by Design (QbD) initiative brought a paradigm shift to pharmaceutical manufacturing and leading manufacturers have realised improved processes after adopting QbD. Raman spectroscopy is an established Process Analytical Technology (PAT), enabling QbD and continuous approaches to pharmaceutical manufacturing.1
19 December 2018 | By European Pharmaceutical Review
Keeping up with the latest developments in pharma.
19 December 2018 | By Harald Fischer
Sophisticated hardware and software offer speed and precision. Pharmaceutical development often involves samples in solution or on transparent substrates. For these applications, confocal Raman imaging using an inverted beam path is an especially versatile and powerful investigative method.
18 December 2018 | By European Pharmaceutical Review
This In-Depth Focus covers drop-coating deposition Raman (DCDR) spectroscopy for metabolite profiling and recent developments of Raman spectroscopy for the qualitative analysis of falsified and substandard medicines.
17 December 2018 | By European Pharmaceutical Review
In this issue: Navigating roadblocks to clinical success: decision-making from molecule to clinic, Raman spectroscopy for the qualitative analysis of falsified and substandard medicines, and an overview of risk assessments for elemental impurities: implementation of ICH Q3D guidelines.
13 December 2018 | By WItec GmbH
90 years ago Chandrasekhara Venkata Raman and Kariamanickam Srinivasa Krishnan first documented "A New Type of Secondary Radiation," which then became known as the Raman Effect [1, 2]. Raman spectroscopy is based on this effect and is used for qualitative and quantitative analysis of the chemical components and molecules of…
12 December 2018 | By Thermo Fisher Scientific
The rapid increase in demand for biopharmaceuticals presents manufacturers with unique challenges to ensure quality and regulatory compliance while maintaining supply and production capacity.
