Application note: Representative sampling in process Raman spectroscopy
Raman spectroscopy is an analysis technique that provides a “molecular fingerprint” of the sample, enabling analysis of chemical composition and molecular structure without sample preparation..
As a measurement technique, Raman imparts many benefits in applications from laboratory discoveries to feedback-control in manufacturing.
In situ real-time analysis, compatibility with aqueous systems, non-destructive nature, and high chemical specificity means that the Raman-analysed sample is representative of the process. Because Raman is a non-destructive technique, the same sample measured by Raman can also be measured by other analytical techniques.
These well-known features have been harnessed throughout the pharmaceutical industry for small molecule pharmaceutical manufacturing and bioprocessing.
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