Expert view: Utility of 3D Raman imaging for pharmaceutical studies
Raman microscopy is well suited to pharmaceutical studies, including the analysis of drug delivery systems and their performance.
It is a non-destructive and label-free technique that can qualitatively and quantitatively characterise the molecular composition of liquids, emulsions and tablets. The components’ spatial distribution can be visualised in 2D or 3D. In this way, the homogeneity of a sample can be investigated, and contaminants can be identified and quantified. It is also possible to gain insight into polymorphisms and crystallinity in solids.