Expert View: Eshmuno® CP-FT resin – developed for the flow-through removal of aggregates using frontal chromatography
Eshmuno® CP-FT cation exchange resin is specifically designed to provide efficient removal of monoclonal antibody (mAb) aggregates in the flow-through frontal chromatography mode of operation enabling loading capacities 10-times higher than traditional bind/elute CEX chromatography. It facilitates greater manufacturing flexibility and process intensification while reducing the overall cost for the downstream purification of mAbs.
MAbs are a successful class of therapeutic proteins increasingly used in the biopharmaceutical industry, but the manufacture of safe and effective mAb drug products as well as increasing productivities of upstream processes provides many challenges to downstream purification.
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