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Capsosomes: the revolutionary enzyme carriers

Posted: 1 July 2019 | | No comments yet

Nature can offer inspiration for the synthesis of more effective drug delivery platforms. In this article, Marc Baiget Francesch discusses the potential of capsosomes as a novel, biocompatible, drug delivery system.

capsosomes

In the case of any disease, having access to the right drug can make all the difference and having the adequate drug is one of the most important steps in disease treatment. However, merely having the drug is worthless if it never reaches the site of action. For this reason, equipping pharmaceuticals with a vehicle to make this possible is important; which is why there is a whole field of research around drug delivery. Designing an appropriate drug carrier is not an easy task. The body environment is, in general, very hostile to any substance that is not natural to the organism – the so-called xenobiotics – or that comes from an unusual route of administration. The digestive tract, for example, is an especially tough environment, with different pH areas and lots of proteases lurking in it. These levels of protection are generally a positive feature and one of the reasons we make it through to old age. However, with our body being such an efficient sentinel, it is hard for many drugs to reach its site of action unscathed.











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