Telstar promotes aseptic technology developments for pharma production
At CPhI (Frankfurt, November 5-7 2019), Telstar will be promoting the latest solutions in isolation technology systems, sterilisation and pharmaceutical freeze-drying applications, designed to ensure an aseptic and efficient production of pharmaceutical processes.
The Telstar portfolio also includes integrated turnkey engineering & construction services for process facilities, manufacturing plants, critical installations and laboratories, as well as GMP consultancy for regulatory compliance and IT solutions for regulated processes & logistics management.
Designed to respond to Industry 4.0 challenges in the life science industry, Telstar will endorse their latest innovative smart developments in the process analytical technology field for pharmaceutical freeze-drying systems and aseptic manufacturing processes, together with integrated process equipment and laboratory integrated management systems. A selection of these technologically advanced systems is detailed below.
In the freeze-drying process field, Lyogistics Zero is the only automatic vial loading & unloading system for freeze-drying processes that can be cleaned (CIP) and sterilised (SIP) in place, inside the freeze-dryer chamber.
Lyonuc® is the nucleation induction method developed by Telstar, suitable for any type of freeze dryer that reduces the duration of the primary drying cycle and ensures the uniformity and homogenisation of the vials in all the batches, respecting the product’s morphology and physiochemical properties. Lyomega SV is a new single-vessel GMP production freeze dryer, optimised to maintain conventional work space while making the footprint up to 20 percent smaller than a lyophiliser with standard external condenser configuration. Lyogistics Smart R3 is the new automated inline vial management device able to reject, reintroduce and retrieve vials during the loading/unloading process into pharmaceutical freeze dryers.
To safeguard the integrity of the lyophilised product, Telstar Lyosensing is a versatile process analyser developed to monitor the freeze drying cycle & detect and prevent real and virtual leakages in pharma freeze dryers. Telstar Lyometrics is an innovative soft-sensor temperature monitoring system in GMP industrial freeze dryers with automatic loading/unloading systems designed to provide on-line monitoring of the global batch product temperature during primary drying, without the limitations and interferences imposed by physical probes.
Furthermore, a smart HVAC control system for clean rooms will also be promoted, whose monitoring and controlling capability allows the system to reduce the frequency of air renovation cycles and to reach the maximum level permitted of particles in the room in accordance with GMP classification, while saving over 40 percent in energy consumption, depending on the room operation and use.
The company will also highlight the benefits of the latest sterility test isolators integrated with Telstar’s innovative ionHP+ bio-decontamination system, proven to dramatically decrease cycle times, increase time available for process and reduce running costs, as well as other innovative solutions in isolation technology systems, sterilisation and water & pure steam generation.