Freeze Drying

Linkam highlights the work of Dr Henning Gieseler from the Division of Pharmaceutics at the Friedrich-Alexander University Erlangen-Nuremberg in the field of pharmaceutical freeze drying

25 January 2018 | By Linkam Scientific Instruments Limited

Market leaders in temperature controlled microscopy and established manufacturers of advanced freeze drying microscopes, Linkam Scientific Instruments, report on the work of Dr Henning Gieseler from the Friedrich-Alexander University (FAU) Erlangen-Nuremberg on his research and development activities in the field of freeze drying for the pharmaceutical industry.

A continuous and controlled pharmaceutical freeze-drying technology for unit doses

2 January 2018 | By Jos Corver, Pieter-Jan Van Bockstal, Thomas De Beer

Among the list of over 300 FDA and EMA approved biopharmaceutical products, around 50% are freeze-dried – indicating that freeze-drying is the preferred way of stabilising biopharmaceutical drug products that are unstable in aqueous solution, despite the high cost and long processing time linked to this manufacturing technique.1,2

Paul G Royall

12 September 2017 | By

Senior Lecturer in Pharmaceutics at King's College London

Paul Royall joins European Pharmaceutical Review

12 September 2017 | By Steve Bremer (European Pharmaceutical Review)

Dr Paul Royall, Senior Lecturer in Pharmaceutics at King’s College London, and Programme Director of the MSc in Pharmaceutical Analysis and Quality Control, has joined European Pharmaceutical Review's Editorial Advisory Board.

QA/QC In-Depth Focus

25 August 2017 | By European Pharmaceutical Review

In this In-Depth Focus: Quality control of freeze-dried oral formulations; Regulatory and quality assurance challenges in continuous manufacturing...

Quality control of freeze-dried oral formulations; challenges when developing novel approaches for the delivery of poorly-soluble drugs

22 August 2017 | By Abdulmalik Alqurshi, Paul Royall

A common obstacle encountered in the early stages of drug development is the formulation of poorly water-soluble drugs (PWSDs). One effective approach to improve the dissolution of PWSDs is to render such drugs into their amorphous or disordered form. However, amorphous materials are both physically and chemically unstable, and tend…

Current trends in freeze-drying

21 August 2017 | By Yves Mayeresse

This article reviews the trends in freeze drying highlighted at recent Parenteral Drug Association (PDA) conferences...

The importance of being small: miniaturisation of freeze drying equipment

18 August 2017 | By Henning Gieseler, Margit Gieseler

Developmental activities for freeze-dried products are dictated by the limited availability and high cost of newly developed active compounds, and by Quality-by-Design requirements. Laboratory-scale freeze dryers used for formulation and process development show an excessive variety of designs and instrumentation concepts, making scale-up activities a challenge. The development of miniaturised…

Issue #4 2017 – Digital Version

17 August 2017 | By European Pharmaceutical Review

In this issue: Miniaturisation of freeze drying equipment, driving excellence in premises and equipment management, a guide to ingredients, and much more...

Formulation Development & Delivery In-Depth Focus

29 June 2017 | By European Pharmaceutical Review

In this Formulation Development & Delivery In-Depth Focus: A report on the use of freeze-drying to develop orally disintegrating tablets; a review of mucosal drug delivery; an interview on drug delivery through the skin; and a profile of three analytical technologies used to develop drug delivery systems...

FDA approves cryopreserved formulation of ReNeuron’s candidate

27 June 2017 | By Niamh Marriott (European Pharmaceutical Review)

The FDA has approved the cryopreserved formulation of ReNeuron’s human retinal progenitor cell (hRPC) therapeutic candidate...

Linkam Scientific Instruments Limited

Biopharma Group

Linkam launches a new platform to replicate large scale freeze drying systems

16 November 2016 | By Linkam

Linkam Scientific Instruments, announce the launch of the FDVS platform, a lyophilisation system to replicate large scale freeze drying processes...

Lab M launches MMGA pre-poured media plate

29 July 2016 | By Lab M

Lab M Ltd, a Neogen company, introduces its Pinnacle™ MMGA (ISO), Mineral Modified Glutamate Agar, pre-poured media plate. The new plate is formulation compliant to ISO 16649-1 and performance compliant to ISO 11133 for the recovery of stressed and injured E. coli in food, water and feed samples.