Discover the new µPAC™ C18 capLC column (1 – 15 µl/min) with unrivalled separation power and plug and play connectivity.
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The practice of bottom-up proteomics relies to a large extent on the separation performance that can be achieved with state-of-the art nano LC-MS/MS equipment.
PharmaFluidics’ new product launch steers ‘on-a-chip’ separations of complex biological samples to new heights
PharmaFluidics NV is a game-changing innovator in the field of analytical chromatography. The company has devised a fundamentally new way of performing separations by creating nano-LC columns on a silicon chip...
Whitepaper: Characterising antibody-drug conjugates using micro pillar array columns combined with mass spectrometry (μPAC™-MS)
The use of micro pillar array columns (μPAC™) for characterising antibody-drug conjugates is presented. Kadcyla® (ado-trastuzumab emtansine) and, for comparison, Herceptin® (trastuzumab) tryptic digests were analysed on a 200 cm μPAC™ C18 column and peaks eluting were detected by ultraviolet (UV) spectroscopy and high-resolution mass spectrometry (MS).
Much rests on the further development of bioanalytical technologies which allow the highest level of sensitivity on small samples, and robust, high reproducibility across large populations. Johan Devenyns, CEO PharmaFluidics, explains further...
European Pharmaceutical Review has brought you the most up-to-date and relevant pharmaceutical science for the past 21 years. This anniversary supplement brings you a selection of topical views from across the industry, reviewing progress over that time, as well as looking to the future.
Katrien Vanhonacker, VP Business Development & Sales at PharmaFluidics, explains at the HPLC 2017 meeting in Prague the key technologies behind micro-Chip based Pillar Array Chromatography.The µPAC™ micro-Chip columns enhance the data productivity of Metabolomics, Lipidomics and Proteomics applications on many installed nano-LC/MS systems.