Active Pharmaceutical Ingredient (API)

news

Crystallographic method accelerates drug development

27 March 2018 | By Dr Zara Kassam (European Pharmaceutical Review)

Researchers have developed a novel method that speeds up the process of determining crystal structures of organic salts and significantly reduces the effort required to do so...

news

Programming DNA to deliver cancer drugs

22 March 2018 | By European Pharmaceutical Review

New technology could lead to the development of new cancer therapies...

article

Freeze-dried formulations: a new perspective on reformulating naloxone

30 June 2017 | By Abdulmalik Alqurshi (Taibah University), Ben Forbes (Kings College London), John Strang (National Addiction Centre), Patrick Courtney (tec-connection), Paul G. Royall (Kings College London)

Opioid overdose in the US and in Europe is on the rise, and the role of prescription-sourced drugs such as oxycodone cannot be underestimated...

article

Separation and purification applications for mutagenic impurities

29 June 2017 | By Dave Elder (JPAG Member and David P Elder Consultancy)

Classically, isolation of key intermediates and the resultant active pharmaceutical ingredient (API) has formed the basis of clean up and purification strategies within the pharmaceutical industry...

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Understanding the effect of API changes in pharmaceutical processing

25 February 2017 | By John Gamble (Bristol-Myers Squibb), John Jones (Bristol-Myers Squibb), Mike Tobyn (Bristol-Myers Squibb)

For the pharmaceutical scientist, the journey of an active molecule from the end of its synthetic pathway and crystallisation to its ultimate site of action is a fascinating one, and one that is necessary to understand...