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Microbiology In-Depth Focus 2018
This issue features articles on Burkholderia cepacia complex, culturomics and metagenomics, and evaluation of microbiological purified water trend using two types of control chart.
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Microbiology
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Issue 5, 2018
In this issue: LC-MS multi-attribute methods for the characterising and QC testing therapeutics, integrating data from Quality Control and Production to enable fast and informed decisions, and Solid-state NMR spectroscopy: using freeze drying to predict the stability of biological products.
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Therapeutic cell manufacture could be controlled by molecular exchanger
The Dynamic Mass Spectrometry Probe uses microfluidic technology to help separate compounds of interest from the salts in less than a minute...
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Multicolour 3D images built from 2D using super-resolution microscopy
Researchers have developed a method of exploiting fluorescence in microscopy to generate 3D images of organelles and structures within cells from 2D images...
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Expert view: Environmental monitoring programmes: key tools for risk management
Environmental monitoring programmes are all about risk management. Use of risk management techniques and a thorough understanding of the processes in the laboratory can assist in identifying any problematic areas...
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Whitepaper: Why should you care about Burkholderia cepacia?
The Burkholderia cepacia complex (BCC) species are a group of gram-negative, rod-shaped bacteria that have been shown in recent years to be of concern for patients, and thus for manufacturers of drugs and products that contribute to patient health...
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bioMérieux launches ENDOZYME® II GO, an innovative test for the detection of endotoxins in pharmaceutical microbiology control
bioMérieux, a world leader in the field of industrial microbiological control, announces the launch of ENDOZYME® II GO, a new endotoxin test in the bioMérieux ENDONEXT™ range of recombinant horseshoe crab Factor C (rFC) assays.
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Scientific Poster: Development of cGMP-Ready purification process for advenovirus purification
Large-scale downstream processing of viruses for clinical applications poses challenges different from those for many other biotherapeutics...
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Scientific Poster: From Screening to Small Scale GMP Biomanufacturing: Exploring a simple, unified platform strategy for handling a range of cell culture needs
This poster discusses a process for a 12-week clone development process. The process starts in silico, and progresses through screening and clone selection in 96-deepwell plates up to five liter shaker flasks...
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Sensitive new assay detects hepatitis B infection in single liver cells and serum
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients…
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Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumour tissue
Researchers have developed a highly specific apoptosis assay designed for immunofluorescence microscopy analysis of fixed core needle biopsy specimens...
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Sensitive new assay detects hepatitis B infection in single liver cells and serum
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...
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Microbeads to combat infection show promise in burn wound simulations
A potential alternative to antibiotics, protein-coated beads block bacteria from binding host cells...
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Bacteria therapy shows promise for eczema
Topical treatment with live Roseomonas mucosa was found to be safe for adults and children with atopic dermatitis...
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LC-TEM provides a window into the nanoscale
Researchers create a device that allows more electron beam to pass through liquid samples...
