Case study: Implementation of the SmartCR in an aseptic processing facility

Airflow reduction and energy savings achieved in HVAC compared to conventional systems.

The challenge of reducing HVAC energy consumption and operation costs without negatively affecting the quality of the finished products, ensuring cleanrooms always conform to required specifications

Abstract 

The SmartCR is an innovative flexible solution for cleanrooms that adjusts air changes which reduces energy consumption and operation costs, ensuring cleanrooms always conform to required specifications. The adjustment is done through the HVAC control system, considering inline particle counters, differential pressure transmitters and temperature and relative humidity probes.

This study explains the implementation of the technology in a new aseptic processing facility. In order to evaluate the energy savings reached, the different tests performed are described and the results are compared to conventional HVAC systems. Commissioning and Qualification strategy is also presented.

It demonstrates how the new system effectively responds to the high quality demanding pharmaceutical industry standards, ensuring the stability of the critical parameters of the controlled environment at all times.

Background 

The SmartCR technology has been implemented in the frame of a newly constructed aseptic facility for liquid and lyophilized products, starting from Conceptual Design, followed by a Basic and Detailed Design.