Whitepapers/App Notes/Posters

Brochure: Separate proteins, peptides and glycans faster

Posted: 11 February 2021 | | No comments yet

The BIOshell™ superficially porous particle (SPP) packed columns aid research to understand the subtleties of the molecule being developed.

BIOshell™ columns enable fast and high-resolution separations to resolve the many structural variants that exist in samples of large biomolecules. Applications include:

  • Top-down analysis of intact proteins, monoclonal antibodies (mAbs), and antibody-drug conjugates
  • Bottom-up analysis (peptide mapping) of proteins for primary structure confirmation
  • Middle-up analysis of mAb fragments (light and heavy chains)
  • High resolution separation of released N- and O-linked glycans.


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