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Successful kidney transplants from hepatitis C infected individuals
Transplantation followed by antiviral therapy cured hepatitis C in 100 percent of patients receiving kidneys from infected donors...
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Stem cells to grow new immune system in Crohn’s disease patients
A phase III clinical trial looks to use a patients own stem cells to treat the debilitating disease...
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Senescent cells targeted with new nanocarrier drug delivery system
Senescent, or zombie cells, are being targeted with the development of a new nanocarrier drug delivery system.
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FDA approves new treatment for rare adrenal gland tumours
“Patients will now have an approved therapy that has been shown to decrease the need for blood pressure medication and reduce tumour size in some patients.”
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‘Perfect’ polymer pill proves it can deliver
The crystal structure was found to have a half-life of 24 hours and could last in the bloodstream for more than 96 hours...
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Why are BACE inhibitors failing clinical trials?
Researchers are now looking to identify if BACE1 is involved in adult hippocampal neurogenesis, and responsible for the brains ability to repair itself...
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Protein kinase C-alpha inhibitor reverses destructive nephritis
Inhibiting protein kinase C-alpha was shown to be a pivotal step towards restoring the damage done by nephritis...
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‘Nano-submarines’ to help target headaches and tumours
Tiny drug-filled nanocarriers, termed ‘nano-submarines’, are being developed to boost the targeted treatment of headaches and tumours, without damaging healthy tissue...
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ITI-214 Parkinson’s drug may be useful for heart failure patients
A drug currently in trials for Parkinson's disease has shown promise in treating heart failure, without the risk of dangerous side effects...
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Nanofiber-based wound dressings induce production of antimicrobial peptide
Nanofiber-based wound dressings loaded with vitamin D spur the production of an antimicrobial peptide, a key step forward in the battle against surgical site infections...
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FDA approves Aristada Inito for the initiation of Aristada for schizophrenia
Novel regimen enables physicians to fully dose up to two months of Aristada treatment on day one...
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Researcher uses HPV vaccine to treat patient with skin cancer
Evidence suggests the human papillomavirus plays a role in the development of some types of this skin cancer...
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Can aspirin treat Alzheimer’s?
A study shows low-dose aspirin may aid removal of harmful amyloid plaque in the brain...
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Overcoming unusual challenges in the characterisation of a monoclonal antibodies by LC-MS from early to late stage of development
2 July 2018 | By SCIEX
Different modalities of monoclonal antibodies are pushing the limits of characterization by MS: new critical quality attributes need to be carefully monitored from developability in early phases and then during process development and clinical phases...
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Higher rifampin doses for TB appear more effective with no greater risks
Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, were shown to kill more TB bacteria in sputum cultures without increasing the adverse effects of treatment, according to a recent randomised controlled trial.
