Application note: In-process monitoring of headspace oxygen levels
Posted: 17 February 2021 | Lighthouse Instruments | No comments yet
The need to monitor headspace oxygen levels in parenteral containers arises from the requirement to ensure the stability and potency of oxygen-sensitive product. This application note describes how headspace oxygen levels are monitored during the filling process as an in-process control (IPC) of the purging system used to bring headspace oxygen levels below a required specification. Non-destructive headspace oxygen analysis enables 100 percent (or statistical) inspection of finished product.
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Analytical techniques, Biologics, Biopharmaceuticals, Biosimilars, Chromatography, Formulation, Lab Automation, Manufacturing, QA/QC, Research & Development (R&D), Vaccines