Whitepaper/App Note

Poster: Accelerate antibody drug development with subdomain-specific affinity ligands

Scientists from Thermo Fisher Scientific discuss how the CaptureSelect affinity purification products and analytical tools have been developed for the discovery and manufacturing of therapeutic antibodies, including novel formats such as bi-specific antibodies and Fc-fusion proteins…

The development of novel antibody therapeutics brings new challenges in the purification of these molecules. Standard chromatography resins, such as Protein A, may not result in the most efficient process. Thermo Scientific™ CaptureSelect™ ligands, focusing on alternative antibody domains, enhance the success of your antibody purification process. The affinity resins provide high target purity in a single step, independent of feedstock. In combination with mild elution to protect the target molecule, these resins provide a platform solution to the industry.

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