Application Note: Anthocyanin purification from blackcurrant with SCPC-100
The blackcurrant is the edible berry of a shrub, which usually grows to 1-2 meters and can be found in Northern/Central Europe and Asia.
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Whitepapers & App Notes
App Note: Controlled supersaturation experiments to check the time that additives keep drugs in solution
Controlled Supersaturation experiments provide a way to create supersaturated solutions which can then be monitored to determine the precipitation rate and the time when precipitation starts. This is illustrated using bifonazole, a basic drug with pKa of 6.0.
Technical Sheet: Charles River Accugenix® MALDI-TOF enhancements for bacterial identifications enable improved root cause analysis
Library coverage is often a topic of discussion for microbiologists wanting to know what the impact or relevancy of the Charles River Accugenix® library databases is on the identification of environmental, EM or industrial microorganisms.
Whitepaper: Chemical characterisation of diverse pharmaceutical samples by Confocal Raman Microscopy
Confocal Raman Microscopy (CRM) is extremely useful for drug substance design, for patent infringement and counterfeit analysis.
Whitepaper: Sampling Guidelines for Handheld Raman Measurements; What You Need To Know
As we see increased adoption of Raman Spectroscopy as the technique of choice for the rapid identification of materials, our guidelines tell you what you need to know...
Validation Study of the Vi-CELL™ XR for Automated Cell Counting of Dendritic Cells
The Vi-CELL XR is an automated cell counting and viability analyzer that uses the trypan blue dye exclusion method...
App Note: Benefits of library and identification method transfer capabilities using hand-held Raman spectrometers
Identification of materials using spectral libraries and other multivariate identification methods on hand-held Raman spectrometers has allowed for rapid non-destructive analysis and easy interpretation of results for non-technical users...
App Note: Following the progress of pharmaceutical mixing studies using near-infrared spectroscopy
This free-to-view Application Note shows the possibility to apply near-infrared spectral information for monitoring the pharmaceutical mixing process...
Whitepaper: Duolink® Technology – Illuminating Insight into Protein Interactions by HCS
Alongside established drug target classes, innovative approaches are addressing previously undruggable target classes such as protein–protein interactions.
Whitepaper: Advantages of Online 2D UPLC for MRM Quantification of Therapeutic Monoclonal Antibodies in Serum
This application note demonstrates the development of a two-dimensional chromatographic assay for the quantification of trastuzumab, providing up to a three-fold increase in sensitivity compared to 1D LC/MRM.
Whitepaper: Pharmaceutical excipients identification with handheld Raman
It is critical and required for pharmaceutical manufacturers to have quality control procedures in place to ensure incoming raw materials are both correct and meet sufficient quality standards...
Whitepaper: Managing Copyright Compliance in Life Sciences
Can purchased or free scientific content be reused or shared? Not necessarily, as the free white paper from RightsDirect explains...
Whitepaper: Advantages of 1064nm Handheld Raman
Raman spectroscopy can be used to effectively and efficiently identify and distinguish different materials.
Application Note: Gattefossé SAS – Investigating the lipolysis of lipid nanoparticles: impact on drug release properties
Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC) are colloidal systems of interest for the delivery of poorly water-soluble drugs.
Whitepaper: Content uniformity method development
Dr. Carl Anderson of Duquesne University, Pittsburgh, USA has written a white paper about developing transmission Raman methods for content uniformity analysis as an alternative to HPLC analysis.
