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Mass spectrometry - Articles and news items

MALDI High-Throughput Screening beyond 100,000 Samples per Day in Drug Discovery

Poster note: MALDI high-throughput screening beyond 100,000 samples per day in drug discovery

Whitepapers / 17 November 2015 / Bruker and Novartis

This work focuses on the improvement of MALDI-TOF automation parameters to further increase sample analysis speed in HTS assays to more than 100,000 samples per day…


Fit-for-Purpose Miniature NIR Spectroscopy for Solid Dosage Manufacturing

Webinars, Z Homepage promo / 26 October 2015 /

This webinar discusses how miniaturised spectrometers facilitate testing of different control schemes with the goal of enabling real-time feedback control of continuous manufacturing processes…

Thermo Fisher Scientific

Thermo Fisher Scientific Receives IVDD CE Mark for its Thermo Scientific Prelude MD HPLC, Endura MD Mass Spectrometer and ClinQuan MD Software

Supplier news / 10 September 2015 / Thermo Fisher Scientific

Now available to clinical laboratories in Europe for general in vitro diagnostic use …

Bruker app note September 2015

Application note: High-throughput Screening of Deubiquitylase enzyme (DUB) activity/specificity and inhibitor screening by MALDI-TOF mass spectrometry

Whitepapers, Z Homepage promo / 1 September 2015 / Bruker Daltonik

In biopharmaceutical laboratories, there is a growing need for high-throughput, yet sensitive methodologies to characterize deubiquitylase enzymes (DUBs) and DUB inhibitors…

Webinar Feature Image

Webinar: Increasing Throughput and Sensitivity of LC-MS assays with a focus on MS optimisation and novel LC strategies

Webinars, Z Homepage promo / 13 July 2015 / Sciex

Simplifying peptide quantification with automated optimisation of MRM transitions and advantages of Micro flow LC to maximise LC-MS performance…

Bruker Webinar Feature

Webinar: Accelerating Pharma R&D using Mass Spectrometry and NMR

Webinars / 14 May 2015 / Bruker Daltonics

In this recorded webinar three experts from Bruker Daltonics and University of Dundee introduce novel MS and NMR solutions and its applications in pharmaceutical research…

Chromatography 270x270

Chromatography & Mass Spec

Z Homepage promo / 22 January 2015 /

Chromatography and Mass Spectrometry are powerful techniques that have recently undergone exponential growth in their application. Explore our free-to-view article archive…

Mass-spectrometry based metabolics

Mass spectrometry-based metabolics – an exclusive online-only article from Tun-Li Shen at Brown University

Chromatography, Industry news / 3 July 2014 / Tun-Li Shen, Brown University

Tun-Li Shen provides a brief overview of the gas chromatography mass spectrometry (GC-MS) and liquid chromatography mass spectrometry (LC-MS) instrumentation platforms used in untargeted metabolomics studies…

Mass Spectrometry In-depth focus

Mass Spectrometry: In-depth focus 2014

Chromatography, Issue 2 2014, Supplements / 15 April 2014 / Paul J. Gates, Ioannis Papayannopoulos

In this free-to-view in-depth focus: Some tricks and tools for structural characterisation of natural products using Electrospray mass spectrometry, Mass spectrometry in the biopharmaceutical industry: from the mundane to the cutting edge, and Mass Spectrometry roundtable…


Eliminate tedious sample preparation with laboratory automation from Tecan

Supplier news / 25 March 2014 / kdm communications

Tecan offers a wide range of laboratory automation solutions for mass spectrometry sample preparation, ensuring there is a system to meet your workflow and throughput needs…

Birthe V. Nielsen, Faculty of Engineering and Science, University of Greenwich

Practical considerations in analysing biologically active peptides by Electrospray Ionisation (ESI) Mass Spectrometry

Chromatography, Issue 5 2013 / 22 October 2013 / Birthe V. Nielsen, Faculty of Engineering and Science, University of Greenwich

Neuromodulators such as calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP) act as biomarkers for pain assessment (pre-clinical). These markers can be detected at low concentrations by Electrospray Ionisation (ESI) Mass Spectrometry (MS). Currently, little is known about the factors affecting responsiveness in the ESI process though the response of peptide ions depends heavily on analyte basicity in solution, pKb, sampling and instrumental conditions. Other factors may be equally important, however, not enough is known about the link between peptide characteristics and selectivity in the ESI process. Here, we review our findings on these links to improve the analyte signal and allow robust quantitation of these important peptide biomarkers…

Mass Spectrometry Supplement 2013

Mass Spectrometry: In-depth focus 2013

Chromatography, Issue 2 2013, Supplements / 17 April 2013 / Uwe Christians, Jelena Klawitter, Jost Klawitter, George McLeod, Min Yang

Corticosteroids and mass spectrometry; latest applications using LC/MS3.
Multi-analyte LC-MS/MS assays for the quantification of endogenous compounds during the development of drugs and companion diagnostics…

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