University College London - Articles and news items

UCL Technology Fund invests £1m in gene therapy company, Freeline

Industry news / 20 June 2016 / Victoria White, Digital Content Producer

Freeline is developing and commercialising gene therapies for bleeding and other life threatening or debilitating disorders…

Researchers make cancer immunotherapy ‘breakthrough’

Industry news / 4 March 2016 / Victoria White

Researchers have found the tools necessary to give immunotherapy the precision guidance that patients with cancer so desperately need…

Epilepsy drug shows promise in protecting nerves from damage in MS

Industry news / 26 January 2016 / Victoria White

Researchers from UCL found the anti-convulsant drug phenytoin protected neural tissue in patients with optic neuritis – often the first symptom of MS…

Study prompts rethink on the rise of diabetes in cities

Industry news / 16 November 2015 / Victoria White

New research shows socio-cultural factors including time pressure, commuting time and where you live play significant roles in diabetes vulnerability…

Donepezil may delay residential care for Alzheimer’s sufferers

Industry news / 27 October 2015 / Victoria White

Withdrawing donepezil from people in the advanced stages of Alzheimer’s disease doubles their risk of being placed in a nursing home within a year, according to a UCL study…

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Avacta Analytical partners with UCL as sponsor of their EPSRC Centre for Innovative Manufacturing

News, Supplier news / 14 November 2011 / kdm communications limited

Avacta Analytical is partnering with University College London as an industrial sponsor…

There is more to qPCR than the PCR reaction

Issue 5 2008, Past issues / 29 September 2008 /

The polymerase chain reaction is arguably the most significant technical discovery yet to have been made in the field of molecular biology and genetics, if not all life science. It cannot be overstated how much of an impact this technique has had, resulting in molecular biology becoming an integral part of most biological and medical research fields. PCR is both highly versatile and extremely sensitive, yet with basic training and adherence to key precautions against contamination, it is comparatively simple to perform. However, when conducting PCR, there are a number of additional considerations that are frequently overlooked when investigating the presence or amount of nucleic acid within a sample.

Enthalpic efficiency and the role of thermodynamic data in drug development: possibility or a pipeline dream!

Issue 6 2007, Past issues / 23 November 2007 /

The determination of accurate thermodynamic data for the interactions of biomolecules has been enhanced over the last decade by the use of isothermal titration calorimetric (ITC) instrumentation. These instruments are now standard kits in many biophysical/structural biochemistry laboratories of pharmaceutical companies. Despite this, there is little evidence for the input of thermodynamic data into the drug development process.


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