Inhibition of mutant P53 tumour cells by medicinal plants
4 May 2016 | By Osuntokun Oludare Temitope and Ogunleye Adewale Joseph, Adekunle Ajasin University
The aetiology of tumours is attributed to changes in many internal (molecular) factors, most of which include mutations in several regulatory mechanisms and the loss of cell differentiation. Human isoforms of the p53 protein play a key role in maintaining genetic stability, functioning as active tumour suppressors. However, a mutation…