whitepaper
App Note: JDSU – Fit-for-Purpose MicroNIR Spectrometer
Miniature and cost-effective NIR spectrometers are starting to facilitate QbD adoption...
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Analytical techniques
whitepaper
Application note: Bruker Optik – TANDEM FT-NIR for on-line tablet characterisation
Pharmaceutical manufacturers are required to enhance their critical quality performances. This is being encouraged by the FDA, which is pushing towards using modern process analytical technology (PAT) to ensure the quality of the final product.
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Issue #6 2013 – Digital edition
In Issue #6 2013: PAT in-depth focus, Lab Automation, Proteomics, Next Gen Sequencing, Screening in-depth focus, Microbiology...
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Screening In-Depth Focus 2013
In this Screening In-Depth Focus: Technological and sociological advances in HTS: evolution and revolution?; Flow cytometry as a drug screening platform; Show Preview: High-Content Analysis 2014
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Process Analytical Technology (PAT): In-Depth Focus 2013
In this Process Analytical Technology (PAT) In-Depth Focus: Presenting a rational approach to QbD-based pharmaceutical development: A roller compaction case study, PAT for pharmaceutical spray drying, PAT Roundtable, Show Preview: IFPAC® 2014...
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Laboratory Automation: Liquid handling devices in drug discovery – when, what, why?
15 December 2013 | By Sergio C. Chai, Asli N. Goktug and Taosheng Chen, High Throughput Screening Center, Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital
Liquid handlers are ubiquitous and essential tools in every aspect of the drug discovery arena. Innovations in the past few decades resulted in a sizeable array of devices. With so many choices, it is important to identify appropriate instrumentation for a particular screening strategy, which should be based on unique…
news
BMG LABTECH and InvivoSciences collaborate to accelerate drug discovery in engineered 3D tissues
BMG LABTECH, Inc. - the Microplate Reader Company - and InvivoSciences, Inc. - a leader in stem cell tissue engineering providing a novel solution in first-in-class drug discovery - announced today a strategic collaboration to market the time-dependent fluorescent assessment of engineered 3D heart tissues using advanced microplate reader technologies.…
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Issue #5 2013 – Digital edition
Read the free digital version of Issue #5 2013 of European Pharmaceutical Review magazine...
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Raman spectroscopy In-Depth Focus 2013
In this Raman spectroscopy In-Depth Focus: Raw material identification using dual laser handheld Raman spectroscopy; Raman spectroscopy in support of biotherapeutic production: applications in protein formulation and purification; Raman Spectroscopy Roundtable...
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Practical considerations in analysing biologically active peptides by Electrospray Ionisation (ESI) Mass Spectrometry
22 October 2013 | By Birthe V. Nielsen, Faculty of Engineering and Science, University of Greenwich
Neuromodulators such as calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP) act as biomarkers for pain assessment (pre-clinical). These markers can be detected at low concentrations by Electrospray Ionisation (ESI) Mass Spectrometry (MS). Currently, little is known about the factors affecting responsiveness in the ESI process though the response…
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Cell-based assays for protein-protein interactions
22 October 2013 | By Mark Wade, Center for Genomic Science of IIT@SEMM
Protein-protein interactions (PPI) form the backbone of all cellular signalling networks, and aberrant PPI contribute to the pathology of several diseases. Thus, strategies to identify PPI modulators are expected to be therapeutically beneficial. However, there are very few examples of clinically approved PPI modulators, reflecting the difficulties of identifying effective…
product
Product Hub: Charles River’s Endosafe®-Nexus™
Alan Hoffmeister, Global Field Technical Manager for the Endotoxin and Microbial Detection Division, Charles River, discusses the Endosafe®-Nexus™...
whitepaper
Whitepaper: Content Uniformity Analysis by Transmission Raman – A Return on Investment Analysis
This whitepaper compares resource requirements, operational timesavings and costs between HPLC and TRS methods...
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Issue #4 2013 – Digital edition
Read the free digital version of the August / September edition of European Pharmaceutical Review magazine...
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ICHQ2(R1) Validation of Analytical Procedures – Challenges and Opportunities
The International Conference on Harmonisation (ICH) guideline for the Validation of Analytical Procedures (ICHQ2(R1)) currently covers validation procedures for the four most common analytical tests: identification tests, quantitative tests for impurities, limit tests for the control of impurities and quantitative tests for the active moiety(ies) in APIs (active pharmaceutical ingredients)…
