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Cosentyx (secukinumab)

 

Cosentyx (secukinumab) is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A,[1] and is manufactured by Novartis Pharma AG for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis.

It targets member A form of the cytokine family of interleukin 17, severely inhibiting its functioning. On January 21, 2015, the United States, the federal Food and Drug Administration announced that it had approved secukinumab to treat adults with moderate-to-severe plaque psoriasis. On January 15, 2016, the United States, the federal Food and Drug Administration announced that it had approved secukinumab to treat adults with ankylosing spondylitis, and psoriatic arthritis.