Product Hub: High sensitivity pyrogen testing with the PyroMAT system: make the move to the next MAT generation

Used to detect a broad range of pyrogens in parenteral products including pharmaceuticals, biopharmaceuticals and medical devices, the Monocyte Activation Test (MAT) gives an in vitro alternative to conventional animal testing in accordance with regulatory guidelines.


With our new Mono-Mac-6 cell line-based MAT, we provide a robust, reliable and standardised method for pyrogen detection.

What can you expect from the PyroMAT system?

  • A pyrogen test that ensures the detection of a broad range of contaminants

The monocyte activation test relies on the human immune reaction to pyrogenic contaminants. Using a source of monocytes, this test mimics the activation of monocytes and measures the release of cytokines to quantify the pyrogenicity of the tested sample.

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