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Drug Discovery

 

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Issue #1 2018 – Digital Version

27 February 2018 | By

In this issue: DNA microarray for detecting, identifying and determining antimicrobial-resistant bacteria; the advantages of single-use technology and a framework for an implementation strategy; risk management when designing chemical safety assessments for pharmaceutical packaging systems.

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Rational drug design: How far have we come?

8 January 2018 | By

From the early use of Hansch parameters and Topliss Trees to today’s computational structure–activity techniques, medicinal chemists have long sought to rationalise drug design to find the quickest and most resource-efficient route to market. But while modern strategies are more reliant on statistical algorithms and vast data libraries, these founding…