This application note presents correlative Raman Imaging and Scanning Electron (RISE) microscopy as a useful tool for investigating the fine structure and chemical composition of pharmaceutical samples.
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Expert view: Investigating drug carriers and in vitro models with advanced analytical imaging techniques
Dr Maike Windbergs discusses the use of Raman imaging in pharmaceutical research and the potential of combining different analytical techniques.
The application of tip-enhanced Raman spectroscopy (TERS) no longer needs to be hampered by a lack of understanding of optical parameters, thanks to new technique, say researchers.
Researchers have developed a highly sensitive technique for probing molecules that they say could enable new applications in the fields of spectroscopy.
The US FDA will fund a research project using Raman spectroscopy and mass spectrometry to study drug delivery via the skin.
Researchers have created targeted, modifiable nanoparticles which could be combined with pharmaceuticals as a form of drug delivery to treat cancer.
Since it was discovered in the 1920s, Raman spectroscopy has been used in pharmaceutical research as a non‐invasive way to provide chemical and structural information in situ, without any staining or complicated sample preparation. Nikki Withers spoke to Professor Kishan Dholakia to hear more about its use in industry and…
Scientists have discovered that liposomes can translocate through the blood brain barrier following stroke and may be able to get drugs to the lesions to stop further damage.
Dr Carsten Hopf and his team are using MALDI imaging in several applications, including drug metabolite and formulation distributions in tissues. This article investigates how this content-rich technique is enabling researchers to gain unique insights to facilitate faster and better drug discovery.
Scientists have developed microrobots that can deliver medication to specific spots inside the body while being controlled from outside the patient.
Researchers have developed a model that describes how antibody solutions separate into different phases and could be used to anticipate the stability and shelf-life of drugs.
Analytical techniques for QA/QC purposes are integral to the safe production of therapeutics. This in-depth focus looks at Raman spectroscopy for amorphous phase analysis and discusses the viable but non-culturable (VBNC) state of bacteria in environmental monitoring.
Researchers have developed a microscope that may provide insight into how safely and effectively a drug will perform in the body...
For decades, near-infrared (NIR) spectroscopy has been an invaluable tool within the laboratory and, interestingly, despite all the excellent instrumentation and technologies introduced for process control, NIR is still the most popular and mature technique available. This article will discuss the impact of NIR in pharmaceuticals from the perspective of…