news
Mass spectrometry identifies biomarkers of COVID-19 disease severity
Researchers have identified 27 biomarkers that could be used to predict the course of SARS-CoV-2 infection and whether a patient with COVID-19 will become severely ill.
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Mass Spectrometry
article
Native liquid chromatography coupled to mass spectrometric analysis for the assessment of higher order structures of proteins
The accurate measurement of the molecular mass of proteins is an essential component of protein characterisation. In this article, Ioannis Papayannopoulos discusses the applications of native protein chromatography coupled to mass spectrometry to enable the characterisation of tertiary structures and non-covalent interactions.
news
Raman spectroscopy and mass spectrometry to be used in study of topically applied drugs
The US FDA will fund a research project using Raman spectroscopy and mass spectrometry to study drug delivery via the skin.
news
Protein engineering market predicted to be worth $3.9 billion by 2024
A report on the protein engineering market suggests it will grow at a CAGR of 12.4 percent, primarily due to protein-based drugs and pharmaceutical company development.
news
Rise in pharmaceutical applications to increase demand for mass spectrometers in Europe
Researchers predict that the market for mass spectrometers will be worth $1.9 billion by 2025 due to demand for faster and more accurate technology.
whitepaper
Application note: Non-targeted host cell protein monitoring in downstream process samples using micro Pillar Array Columns combined with mass spectrometry (μPACTM-MS)
This whitepaper reports on the use of μPAC™ in combination with MS for the characterisation of HCPs and their monitoring during downstream processing.
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Expert view: The future of biologics quality – multiple attribute methodology
Characterisation and quality control of proteinbased biotherapeutics has historically been a lengthy and challenging process due to their complexity and inherent heterogeneity.
news
FDA releases statement on ranitidine testing results
The FDA has issued a statement on the results from ranitidine medication testing for nitrosamines, saying that they contain no more NDMA than smoked meats.
news
Global LC-MS market to exhibit CAGR of 6.9 percent
Research has found that the worldwide LC-MS market will be worth $2750 million by the end of the forecast period in 2024.
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Advanced MALDI imaging breaks ground in pharmaceutical research
Dr Carsten Hopf and his team are using MALDI imaging in several applications, including drug metabolite and formulation distributions in tissues. This article investigates how this content-rich technique is enabling researchers to gain unique insights to facilitate faster and better drug discovery.
article
Assessing host cell protein contamination in biotechnological products
Purification of a drug from host cell protein contaminants can be challenging, with low-level contamination often remaining after purification. Vanda Dolabela de Magalhães shares discussions on the subject from six Brazilian companies working in the biotech field.
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Analytical methods used in obtaining higher order structure information from protein therapeutics
The efficacy, safety and pharmacokinetic properties of a protein therapeutic substantially depend on the molecule having the right structure. This article reviews current methods used for obtaining higher order structure information of biotherapeutics.
video
Video: Introducing the new SYNAPT XS High Resolution Mass Spectrometer
Introduced at ASMS 2019, the new SYNAPT XS provides ultimate flexibility offering greater freedom of analytical choice to support scientific creativity and technical success for any application.
video
IonBench: Manufacturer of mobile benches for mass spectrometry and liquid chromatography
Overview on how ionBench products can help LC/MS users with dedicated furniture for their instrumentation
