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Effectiveness of HPV vaccines Cervarix and Gardasil under question
Analysis of the designs of Phase II and III efficacy trials for HPV vaccines suggest they overstated their effectiveness against cervical cancer, according to researchers.
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Viruses
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Nanoparticle gene therapy drug delivery for paediatric brain cancer tested in mice
A study has shown that PBAE nanoparticles could replace viral vectors in gene therapies and provide a safe treatment option for paediatric brain cancer patients.
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Report indicates seasonal influenza vaccine market in Asia will reach $1bn by 2028
A new report indicates that drug launches and new formulations will drive the growth of the seasonal influenza vaccine market in China, India and Japan from $914m in 2018 to $1.05bn in 2028.
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New breakthrough can effectively deliver medications into the brain
Scientists have found a way to effectively transport medication into the brain which could lead to improved treatments for neurological and neurodegenerative diseases.
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Antiviral drug not beneficial for reducing mother-to-child transmission of hepatitis B
Tenofovir disoproxil fumarate (TDF) does not significantly reduce mother-to-child transmission of hepatitis B virus when taken during pregnancy and after delivery.
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Gene-based Zika vaccine is safe and immunogenic in healthy adults
Results from two Phase 1 clinical trials show an experimental Zika vaccine is safe and induces an immune response in healthy adults.
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Virus-like particle vaccine protects against RSV vaccine-enhanced respiratory disease
Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory diseases...
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New vaccine offers hope for pneumonia
Scientists are developing a vaccine by targeting strains of S. pneumoniae...
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Flu vaccine found to be ineffective in leukaemia patients
Leukaemia patients who were vaccinated against influenza were just as likely as their unvaccinated peers to develop flu, suggesting that additional steps are necessary to protect high-risk individuals...
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Vaccine demonstrates significant efficacy against severe rotavirus
Results from a Phase 3 efficacy study in India of the rotavirus vaccine Rotasil showed the vaccine to be safe, against severe rotavirus gastroenteritis...
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Poliovirus therapy induces immune responses against cancer
Investigational therapy directly kills tumour cells and unmasks them to the body's defences.
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Zika virus shown to kill brain cancer stem cells
Research published in The Journal of Experimental Medicine suggests potential treatment for glioblastoma
whitepaper
Whitepaper: Development of an Efficient Manufacturing Process for Adenovirus
Large-scale downstream processing of viruses for clinical applications poses challenges different from those for many other biotherapeutics. These challenges mostly arise from the size and complexity of the virus...
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Influenza virus mutations prevented during vaccine production
Duke researchers used a bivalent virus from chicken cells that packaged twice as much protein as a monovalent virus, and vaccinated mice with either the bivalent or monovalent vaccine
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Study finds mobile phones used by hospital staff harbour viruses
21 June 2016 | By Victoria White, Digital Content Producer
A study from University Hospital of Saint-Étienne in France reveals that mobile devices are often also contaminated by viral RNA...
