news
Protein kinase C-alpha inhibitor reverses destructive nephritis
Inhibiting protein kinase C-alpha was shown to be a pivotal step towards restoring the damage done by nephritis...
List view / Grid view
Drug Targets
news
FDA approves the first drug with an indication for treatment of smallpox
The US Food and Drug Administration has approved TPOXX (tecovirimat), the first drug with an indication for treatment of smallpox...
news
Plerixafor may protect against smoke-related COPD symptoms
A drug used in stem cell therapy to treat certain cancers may also protect against cigarette smoke-induced lung injury...
news
Flu’s response to Xofluza explored
Scientists are now investigating the Xofluza mode of action in detail and have uncovered possible mechanisms by which viral resistance to it could emerge...
news
BCG vaccine leads to long-term blood sugar improvement in type 1 diabetes
A study has found a novel mechanism underlying stable, durable blood sugar control...
news
Researchers find combination can enhance ipilimumab immunotherapy
Anti-CTLA-4 treatment triggers immune-suppressing EZH2 on T cells; clinical trial open...
news
SMC approves Xermelo for carcinoid syndrome diarrhoea
Scotland is the first country in the UK to enable patients, battling this serious and debilitating condition, access to a new treatment option...
news
Better outcomes for patients using single-pill combination for hypertension
Findings may represent simple and potentially low-cost intervention...
news
Talazoparib shows promise for early-stage BRCA+ breast cancer patients
Once-daily oral pill could replace preoperative chemotherapy in patient population if validated in larger trials...
news
Immunosuppressant drugs may protect against Parkinson’s
People who take immunosuppressants are less likely to develop Parkinson's disease...
news
Ibrutinib may benefit glioblastoma patients
An FDA-approved drug for lymphoma and leukaemia may also help treat the most common - and deadliest type of brain tumour...
news
FDA accepts Larotrectinib New Drug Application and Grants Priority Review
The FDA has accepted the NDA and granted Priority Review for larotrectinib for advanced or metastatic solid tumours harbouring a NTRK gene fusion...
news
AIBP injection alleviates chemotherapy pain for months in mice
Protein inhibits inflammatory response underlying chronic pain processing may provide an alternative to opioids for severe, persistent pain...
news
Drug-delivering nanoparticles could help fight brain cancer
Nanoparticles carrying two drugs can cross the blood-brain barrier and shrink glioblastoma tumours...
news
FDA approves Palynziq for PKU, a rare and serious genetic disease
Novel enzyme therapy for adults with PKU who have uncontrolled blood phenylalanine concentrations with current treatment...
