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Novel COVID-19 test could significantly reduce testing time
The new COVID-19 test, called RTF-EXPAR, was able to accurately detect the presence of SARS-CoV-2 viral RNA in under five minutes.
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HTS (High Throughput Screening)
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Bioprocessing & Bioproduction In-Depth Focus 2020
In this in-depth focus learn about the development and implications of a novel high-throughput method for glycoanalytics and how taking a full-ecosystem approach to microbiome restoration could improve patient survival.
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Product Hub: High-throughput experimentation made easier with Katalyst D2D
Katalyst D2D is a new software application from ACD/Labs that makes the planning, execution and analysis of high-throughput, parallel experiments easier than ever before. Katalyst is a web-based digital environment that integrates with existing informatics systems, lab automation hardware, analytical instrumentation and automated execution systems for an efficient, streamlined workflow.
Whitepapers/App Notes/Posters
Application note: Improving the efficiency of catalyst screening in drug substance development
Herewith ACD/Labs presents their web-based software solution to the multiple challenges experienced in screening workflows; offering effective support for high-throughput catalyst screening.
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Single cell technology company Dolomite Bio celebrates a successful first year
28 March 2017 | By Dolomite Bio
Dolomite Bio, a brand of Blacktrace Holdings Limited, celebrated the first anniversary of its launch on March 1st, marking the end of a fruitful year in business...
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IntelliCyt Cy-Clone™ PLUS
27 March 2017 | By IntelliCyt Corporation
Cy-Clone PLUS together with the iQue Screener PLUS platform uses the power of high throughput flow cytometry...
Whitepapers/App Notes/Posters
Application note: Raman-based high-throughput screening for version and polymorph identification
In this application note, find out more about the RamanRxn1™ High Throughput Screener (HTS) from Kaiser Optical Systems, Inc...
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Empower your research with Tecan’s Spark® 20M multimode reader
25 January 2016 | By Tecan
Tecan has launched the Spark® 20M multimode microplate reader, offering tailor-made solutions to suit virtually any drug discovery or advanced life science research application...
Whitepapers/App Notes/Posters
Poster note: MALDI high-throughput screening beyond 100,000 samples per day in drug discovery
This work focuses on the improvement of MALDI-TOF automation parameters to further increase sample analysis speed in HTS assays to more than 100,000 samples per day...
Whitepapers/App Notes/Posters
Application note: High-throughput Screening of Deubiquitylase enzyme (DUB) activity/specificity and inhibitor screening by MALDI-TOF mass spectrometry
In biopharmaceutical laboratories, there is a growing need for high-throughput, yet sensitive methodologies to characterize deubiquitylase enzymes (DUBs) and DUB inhibitors...
article
Pharmaceutical salts of small molecule drugs: opportunities and challenges
28 October 2014 | By Axel Becker, Scientist, Merck KGaA
Over the past decades, pharmaceutical drug development has undergone some significant changes, a prominent example for this being the emergence of biomolecular drugs (New Biological Entities, NBEs) such as antibodies and peptides. However, classical small molecule drugs (New Chemical Entities, NCEs) are far from being a dying species, and in…
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Screening In-Depth Focus 2013
In this Screening In-Depth Focus: Technological and sociological advances in HTS: evolution and revolution?; Flow cytometry as a drug screening platform; Show Preview: High-Content Analysis 2014
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Laboratory Automation: Liquid handling devices in drug discovery – when, what, why?
15 December 2013 | By Sergio C. Chai, Asli N. Goktug and Taosheng Chen, High Throughput Screening Center, Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital
Liquid handlers are ubiquitous and essential tools in every aspect of the drug discovery arena. Innovations in the past few decades resulted in a sizeable array of devices. With so many choices, it is important to identify appropriate instrumentation for a particular screening strategy, which should be based on unique…
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Pharmaceutical proteomics: a journey from discovery and characterisation of targets to development of high-throughput assays
15 December 2013 | By Joerg Reinders, Institute of Functional Genomics, University of Regensburg
Proteomics has evolved during the last few years from a time-intensive, cost-intensive and hard-to-reproduce technique in basic research to a versatile and reliable tool in various areas of pharmaceutical research. The exploding progress in mass-spectrometry-compatible protein and peptide-separation methods led to the development of new approaches particularly suited for monitoring…
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Molecular drug targets in autophagy
19 April 2011 | By Robin Ketteler, MRC LMCB, University College London
Autophagy is a cellular stress response to diverse stimuli such as starvation, infection and DNA damage. Autophagy plays important roles in the progression of various diseases including cancer, neurodegenerative diseases and Crohn’s disease. Despite recent advances in our understanding of the autophagy machinery, surprisingly little effort has been undertaken towards…