news
Silver nanoparticles improve molecular detection in Raman spectroscopy
Researchers have improved molecular detection at low concentration levels by arranging nanoparticles on nanowires to enhance Raman spectroscopy....
List view / Grid view
Analytical techniques
article
A continuous and controlled pharmaceutical freeze-drying technology for unit doses
Among the list of over 300 FDA and EMA approved biopharmaceutical products, around 50% are freeze-dried – indicating that freeze-drying is the preferred way of stabilising biopharmaceutical drug products that are unstable in aqueous solution, despite the high cost and long processing time linked to this manufacturing technique.1,2
news
Seasonal images reflect stem cells science
University of Southampton postgraduate researcher Catarina Moura creates seasonal images from stem cells as part of her investigation into new optical techniques to monitor the cells' development.
article
21st Anniversary Supplement
European Pharmaceutical Review has brought you the most up-to-date and relevant pharmaceutical science for the past 21 years. This anniversary supplement brings you a selection of topical views from across the industry, reviewing progress over that time, as well as looking to the future.
article
Raman In-Depth Focus 2017
This In-Depth Focus looks at photobleaching profile of Raman peaks and surface-enhanced Raman spectroscopic sensing of glucose.
article
What do we need from PAT?
Pharmaceutical manufacturing in the modern era is facing unprecedented demands, including in-depth scrutiny of production methodology, and inefficiencies in current practices with respect to waste, energy usage and time management. Coupling this with increased complexity in the manufacture of newer products and the decline of blockbuster drugs, results in an…
article
Surface-enhanced Raman spectroscopic sensing of glucose
The small normal Raman cross-section of glucose is a major challenge in its detection by surface enhanced Raman spectroscopy (SERS) for medical applications, such as blood glucose level monitoring of diabetic patients and evaluation of patients with other medical conditions, since glucose is a marker for many human diseases. Here…
article
Photobleaching profile of Raman peaks and fluorescence background
Laser-induced fluorescence is the most common source of interfering baseline signal encountered in Raman measurements. It shows itself as a slowly changing background in a spectrum. One of the challenges in the successful use of Raman spectroscopy is to extract Raman signatures from this, orders of magnitude stronger, broadband fluorescence…
article
Issue #6 2017 – Digital Version
This issue celebrates European Pharmaceutical Review's 21st birthday through 21 interviews with leading lights from across the pharmaceutical industry...
news
Plasmonic biosensors enable development of new easy-to-use health tests
Researchers have developed a biosensor that can detect diseased exosomes, important indicators of various health conditions...
whitepaper
Application Note: Benefits of web-based solutions applied to eve for bioprocess software
The development of powerful, modern browsers and the proliferation of mobile platforms has altered the way in which programs run and where data is stored...
whitepaper
Application note: Raman Hyperspectral Imaging: an essential tool in the pharmaceutical field
Resulting from the combination of Raman spectroscopy and optical microscopy, Raman hyperspectral imaging has proven to be an indispensable tool in the pharmaceutical field. This article will broach a number of Raman hyperspectral imaging applications that were developed in our laboratory, to demonstrate the significance of the technique...
whitepaper
Whitepaper: Improved efficiency and lower costs using simultaneous testing for TOC and conductivity
Total Organic Carbon (TOC) and conductivity measurements are required for compendial water quality...
whitepaper
Whitepaper: The ‘workhorse technique’ that is still enabling scientists to break new ground after 70+ years
Electron paramagnetic resonance (EPR) spectroscopy is the only method for the direct detection of species that have unpaired electrons...
whitepaper
Whitepaper: Cleaning validation – what do you need to consider to ensure a successful outcome?
This white paper discusses the over-arching strategy for performing a successful cleaning validation, with detail on some of the key factors to consider at both the manufacturing, microbiological and analytical stages, highlighting many common pitfalls to avoid..
