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Niclosamide could lead the fight against Parkinson’s disease
Drug molecule in tapeworm medicine activates protein implicated in the development of Parkinson's disease...
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Abatacept improves survival in patients with acute GvHD
A drug used to treat rheumatoid arthritis improves survival after hematopoietic stem cell transplant...
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Meeting access challenges with adaptive trial designs
With access challenges even after successful but costly development programmes, the industry is under pressure to speed up the clinical development process and produce more for less. Adaptive trial designs, more collaborative working and data sharing could provide a solution in the area of cancer immunotherapy, says Jacqueline Karmel, principal…
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FDA approves first once-monthly buprenorphine injection for OUD
FDA approves first once-monthly buprenorphine injection, a medication-assisted treatment option for moderate-to-severe opioid use disorder...
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A risk factor for drug-induced skin disease identified
Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.
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Gene-based Zika vaccine is safe and immunogenic in healthy adults
Results from two Phase 1 clinical trials show an experimental Zika vaccine is safe and induces an immune response in healthy adults.
whitepaper
Whitepaper: Extractables and leachables testing – A risk based approach
Pharmaceutical products are in contact with many external components during both manufacture and usage and small amounts of chemicals may leach from these components with a potential health risk to the patient...
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Synthetic-biological hybrid nanocapsule combats diseased cells
A new drug delivery system could provide a smart technology for the targeted treatment of a variety of serious diseases...
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Neoantigen-based immunotherapy targets misshapen protein in DIPG
Children with an extremely deadly form of brain cancer may benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found on cancer cells...
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PAC-1-temozolomide combination shows promise for anaplastic astrocytoma
A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma...
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GPS-enabled nanoparticles seek and destroy cancer stem cells
Researchers have developed tiny drug-laden nanoparticles that can seek and destroy cancer stem cells...
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Lung function of COPD patients improved with Ultibro Breezhaler
Novartis has announced positive results from the FLASH study examining the safety and efficacy of directly switching COPD patients from Seretide to Ultibro Breezhaler...
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Pembrolizumab shows hope for cancerous gestational trophoblastic disease
An immunotherapy drug can be used to cure a rare type of cancer arising from pregnancy when existing treatments have failed...
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Virus-like particle vaccine protects against RSV vaccine-enhanced respiratory disease
Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory diseases...
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Antimalarial drugs could support existing cancer treatments
Chloroquine and hydroxychloroquine could make cancer treatments more effective...
