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Moffitt Cancer Center

Checkpoint inhibitor combination shows promise in Merkel cell carcinoma

13 September 2022 | By Hannah Balfour (European Pharmaceutical Review)

Dual checkpoint inhibitor blockade could be a promising first-line and salvage therapeutic option for advanced Merkel cell carcinoma, say researchers.

3d illustration of CAR T cells attacking cancer cells and releasing cytokines - idea of CAR T Therapy

news

CAR T therapy achieves high remission rate in acute lymphoblastic leukaemia trial

16 June 2021 | By Hannah Balfour (European Pharmaceutical Review)

Trial data shows 71 percent of adult B cell acute lymphoblastic leukaemia patients receiving Tecartus® autologous anti-CD19-transduced CD3+ cell infusion achieved complete remission.

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Combining pacritinib with sirolimus-based GvHD prophylaxis may improve efficacy

24 March 2021 | By Hannah Balfour (European Pharmaceutical Review)

Phase I results suggest adding pacritinib to sirolimus and low-dose tacrolimus could be beneficial in preventing graft-versus-host disease (GvHD).

news

Durvalumab improves survival of non-small cell lung cancer patients

28 September 2018 | By Iqra Farooq (European Pharmaceutical Review)

Moffitt researchers conducted a Phase III trial which found durvalumab to increase the survival of patients with non-small cell lung cancer...

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Combining drugs that target BRAF and HSP90 shows success for melanoma patients

24 April 2018 | By European Pharmaceutical Review

Scientists have tried combining drugs in an effort to prevent resistance development that eventually leads to cancer regrowth in melanoma patients.

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Researchers use novel methods to determine drug uptake for tumours

14 March 2018 | By European Pharmaceutical Review

Researchers at the Moffitt Cancer Center in Florida have combined single-cell imaging of cancer cells in mice with mathematical modelling to establish which drug characteristics determine its efficacy.

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Rare melanoma type highly responsive to immunotherapy

12 January 2018 | By European Pharmaceutical Review

Moffitt Cancer Center researchers have discovered that patients with desmoplastic melanoma are more responsive to immune-activating anti-PD-1/PD-L1 therapies than previously assumed.

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Researchers discover new targets for approved cancer drug ceritinib

11 October 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

New study shows ALK inhibitor ceritinib may have the ability to be used for more than ALK-rearranged non-small cell lung cancer...

news

Improved vaccine protects against nine types of HPV

7 September 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

Scientists have developed an improved vaccine commonly associated with cervical cancer...

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Moffitt Cancer Center