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FDA approves new administration route for Phesgo to treat breast cancer
The FDA has given approval to Phesgo for injection under the skin to treat HER2-positive breast cancer, meaning it can be administered at home by a healthcare professional.
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Drug Delivery Systems
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How implantable systems and microparticle depot injections are meeting the needs of long-acting drug delivery
Implantable systems and microparticle depots are used in many areas of drug delivery to release medicines at a controlled rate within the body. The use of these long-acting dosage forms eliminates the need for frequent administrations via traditional routes of administration, which ensures patient compliance and results in improved outcomes.…
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Formulation, Development & Delivery In-Depth Focus 2020
The articles in this in-depth focus outline the advantages of repurposing existing drugs for new indications and reveal why implantable systems and microparticle depots as drug delivery systems can aid patient compliance.
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European Pharmaceutical Review Issue 3 2020
In this issue is a discussion on the promise of virally vectored DNA and mRNA vaccines to combat COVID-19 as well as articles on how packaging could help to ensure patient adherence, regulatory issues for medicines and diagnostics during the pandemic and the benefits of digitalising the pharmaceutical supply chain.…
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Video: Vanquish core video infographic
The Vanquish Core is a powerful system designed for dependability whilst giving you exceptional results in an intuitive and easy to use instrument.
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Application note: Nitrosamines by GC-MS in Valsartan
Determination of nitrosamines including gentoxic NDMA analysed by GC-MS in Valsartan using direct injection and headspace methods, below required LOD.
whitepaper
Infographic: Eight reasons to use Thermo Scientific for HPLC
Separate your science from the status quo, advanced solutions offering superior retention time stability, flexible integration and minimal maintenance.
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Brochure: Thermo Scientific Charged Aerosol Detectors
Charged aerosol detection is a technique capable of measuring any non-volatile and many semi-volatile species in a pharmaceutical applications.
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Researchers synthesise red blood cells with ability to deliver drugs
Artificial red blood cells have been created by researchers which can be used as normal cells or to carry drugs around the body.
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Microneedle system developed to deliver mesenchymal stem cells
A group of researchers has developed a microneedle delivery system for mesenchymal stem cells, which showed success in mice skin wound models.
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Anti-cancer drug delivery: peptoid-coated DNA origami
Scientists have designed and synthesised chains of molecules for the purpose of drug delivery with a precise sequence and length to protect DNA nanostructures from degradation under biomedically relevant conditions.
whitepaper
Whitepaper: Establishing the proper PH range for aqueous simulating solvents used in extractables profiling
This whitepaper considers the chemical properties of commonly encountered acidic and basic extractables and uses these properties to address questions about establishing the proper pH (or proper pH range).
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Attenuated diptheria toxin developed by researchers as novel form of drug delivery
A new potential platform for drug delivery has been created by researchers using attentuate diptheria toxin, which can enter cells and escape the endosome.
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Brochure: Capsugel® R&D portfolio
The Capsugel® R&D portfolio features capsule and related service solutions for faster research and development during pre-clinical and clinical stages.
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Application of liquid chromatography in characterisation of lipid nanoparticle-based oligonucleotides
Duplex oligonucleotides (OGN) with lipid nanoparticles (LNPs) as delivery vehicles for different therapeutic indications are of great interest in pharma, exemplified by the recent approval of Onpattro from Alnylam Pharmaceuticals. Liquid chromatography is an essential analytical technique in the characterisation of LNPs containing OGNs. This brief review is intended to…
