Genomics

UK accounts for 12 percent of global cell and gene therapy clinical trials

17 January 2020 | By Victoria Rees (European Pharmaceutical Review)

New research has found that the cell and gene therapy clinical environment in the UK has encouraged commercial sponsorship from around the world.

New drugs more likely to be approved if backed up by genetics, says study

13 December 2019 | By European Pharmaceutical Review

A new study could aid pharmaceutical companies in their drug development efforts after if found that a drug candidate is more likely to be approved for use if it targets a gene known to be linked to the disease.

Do viability methods detect all viable organisms?

1 July 2019 | By Jeanne Moldenhauer

Many bacterial species have been found to exist in a viable but non-culturable state. Jeanne Moldenhauer discusses this phenomenon and makes suggestions as to why we don’t often see an increase in viable cells when using viability-based methods.

BPSA releases guide to production of cell and gene therapies

25 February 2019 | By BPSA

The Bio-Process Systems Alliance, the primary international industry association for single-use bio-processing, is pleased to announce the release of its latest whitepaper...

NHS announces groundbreaking personalised child cancer treatment

5 September 2018 | By Iqra Farooq (European Pharmaceutical Review)

The NHS has announced a groundbreaking new treatment, CAR-T, for children with leukaemia...

Gene therapy receives Champalimaud Vision Award

4 September 2018 | By European Pharmaceutical Review

The Champalimaud Vision Award has been awarded to research teams for the development of a gene therapy...

Fast-acting cholera vaccine could curb outbreaks

15 June 2018 | By European Pharmaceutical Review

A tricked-out cholera vaccine starts protecting against the deadly disease within a day, experiments in rabbits suggest.

Genome sequencing of first 50,000 UK Biobank participants

6 April 2018 | By European Pharmaceutical Review

UK Biobank has announced a major initiative to sequence the full genomes of 50,000 UK Biobank volunteer participants...

Larotrectinib shows promise in paediatric patients with TRK gene mutations

5 April 2018 | By Dr Zara Kassam (European Pharmaceutical Review)

A new cancer drug has proven safe and effective for paediatric patients with a rare tumour gene mutation...

Does genome sequencing increase downstream costs?

26 March 2018 | By European Pharmaceutical Review

A pilot study has found that whole genome sequencing of healthy individuals and cardiology patients did not increase health care spending outside of the sequencing costs.

Blood and urine tests developed to indicate autism in children

20 February 2018 | By Dr Zara Kassam (European Pharmaceutical Review)

International researchers believe that their new blood and urine tests which search for damage to proteins are the first of their kind to detect early autism spectrum disorders...

Agilent Technologies

Blood-based epigenetic may hold clues to autism

24 October 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

Epigenetic data reveals immune-response pathways that may prove critical to understanding autism...

PI3K inhibitors show hope for rare bone cancers

12 October 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

Scientists have used genome sequencing to gain a better understanding of the biology underlying chordoma...

Neratinib defeats the Ras genes notorious for causing cancer

11 October 2017 | By Dr Zara Kassam (European Pharmaceutical Review)

Breast cancer drug neratinib has been found to block the function of the Ras genes which are among the first to be linked to cancer development...