DNA nanostructure stabilisation could enable translation into clinical use
Stabilising DNA nanostructures using glutaraldehyde to tether an electrostatic PEGylated oligolysine net to the DNA enabled them to survive degradation in animal models.
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Stabilising DNA nanostructures using glutaraldehyde to tether an electrostatic PEGylated oligolysine net to the DNA enabled them to survive degradation in animal models.
Scientists have developed an innovative nanocarrier that can selectively target and deliver a chemotherapy payload to cancer cells without adverse effects on healthy cells.
Researchers have created targeted, modifiable nanoparticles which could be combined with pharmaceuticals as a form of drug delivery to treat cancer.
Chemists have synthesised a single catalyst, able to perform multistep cascades of chemical reactions to produce a pharmaceutical product.
Scientists have developed a highly sensitive material that can analyse multiple environmental parameters simultaneously, which could be used in drug delivery.
A study has shown that PBAE nanoparticles could replace viral vectors in gene therapies and provide a safe treatment option for paediatric brain cancer patients.
A proof-of-concept nanorobot design could be used to target cancer cells by their glucose consumption and deliver a drug payload in response to tumour interaction.
Nanobots have the capacity to precisely release drugs in the body for targeted delivery. Victoria Rees investigates several new developments in the nanobot field, to discover recent advances and how nanobot drug delivery systems may continue to evolve.
A new technique has been demonstrated that will control the size and shape of nanoparticles which could lead to their use as a form of drug delivery.
A team has developed a microrobot that is effective at targeting specific areas, so could be used in hyperthermia therapies when treating cancers.
This article covers the analytical criteria that apply to Bacterial Endotoxin Testing (BET) using Limulus Amebocyte Lysate (LAL) or recombinant Horseshoe crab Factor C (rFC) for the bioactivity determination of endotoxin in aqueous solutions, such as pharmaceuticals and medical device extracts. It explains the importance of these criteria for accurate…
In the future, venomous snakebites could be treated using nanoparticles to bind the venom toxins and prevent them from spreading around the body...
Researchers have developed a fluorescing nanoparticle capable of finding tumours, lighting up upon arrival and being activated with light to generate heat to destroy the cancer cells...
Scientists have found a way to effectively stop internal bleeding by magnetically-driven nanoparticles containing thrombin...
New injectable delivery system can slowly release drug carriers for months...