Application Note: Optical pH measurement of contact lens solutions
Various sources estimate that more than 125 million people worldwide wear contact lenses – their popularity having grown appreciably as lenses have become safer and more effective...
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Whitepapers & App Notes
Whitepaper: Do you know what’s going in? Analysing tablets by NIR spectroscopy
Drug analysis needs to be cost effective without compromising on accuracy...
Whitepaper: pAVEwayTM – microbial expression system for the efficient large scale production of therapeutic proteins
pAVEway™ is an innovative expression system in E. coli that enables rapid creation of novel recombinant strains and the development of downstream processes that ensure industry leading product titres and efficient scale-up of the production of proteins of therapeutic utility...
Application note: Raman Hyperspectral Imaging: an essential tool in the pharmaceutical field
Resulting from the combination of Raman spectroscopy and optical microscopy, Raman hyperspectral imaging has proven to be an indispensable tool in the pharmaceutical field. This article will broach a number of Raman hyperspectral imaging applications that were developed in our laboratory, to demonstrate the significance of the technique...
Whitepaper: Improved efficiency and lower costs using simultaneous testing for TOC and conductivity
Total Organic Carbon (TOC) and conductivity measurements are required for compendial water quality...
Whitepaper: The ‘workhorse technique’ that is still enabling scientists to break new ground after 70+ years
Electron paramagnetic resonance (EPR) spectroscopy is the only method for the direct detection of species that have unpaired electrons...
Whitepaper: Perform conductivity measurements in compliance with USP <645>
“Water is the most widely used substance, raw material, or ingredient in the production, processing and formulation of compendial articles...”
Application Note: Elemental Impurities
Metallic contamination in drug products, referred to as elemental impurities, may arise from several sources...
Whitepaper: Cleaning validation – what do you need to consider to ensure a successful outcome?
This white paper discusses the over-arching strategy for performing a successful cleaning validation, with detail on some of the key factors to consider at both the manufacturing, microbiological and analytical stages, highlighting many common pitfalls to avoid..
Whitepaper: Sensitive and flexible bacterial endotoxin testing with the EndoZyme® II Recombinant Factor C Assay using the Synergy™ HTX Microplate Reader
This article covers how the EndoZyme II assay is established, optimised and validated using the SynergyTM HTX Multi-Mode Microplate Reader with Gen5TM software...
Whitepaper: How an integrated development platform can meet the needs of both analytical development and QC teams
This whitepaper explains how an Integrated Development Platform can meet the needs of both analytical development and QC...
Application Note: Stearates verification using a handheld Raman analyzer
In this application, a Principal Component Analysis (PCA) method was found to be successful in identifying the various stearates...
Application note: Representative sampling in process Raman spectroscopy
Raman spectroscopy is an analysis technique that provides a “molecular fingerprint” of the sample, enabling analysis of chemical composition and molecular structure without sample preparation..
Whitepaper: Meeting modern data integrity and compliance requirements
FDA was perhaps understating a point when it said in its April 2016 Draft Guidance: Data Integrity and Compliance with cGMP that the increasing number of data integrity-related cGMP violations identified during its inspections was ‘troubling’...
Whitepaper: Dwell Volume and Extra-Column Volume: What are they and how do they impact method transfer
Method transfer or method scaling across different instrument platforms can be affected by both dwell volume and extra-column dispersion...
