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Antibiotics

Destiny’s SA trial shows fast acting antibiotic too quick for disease resistance

5 September 2016 | By Niamh Louise Marriott, Digital Content Producer

The two-stage clinical trial studied the safety, tolerability, and efficacy of intra-nasally applied exeporfinium chloride gels. Part 1 yielded safety data in eight volunteers and allowed progression to Part 2 in 48 healthy volunteers with colonised nasal Staphylococcus aureus (SA) bacteria. Part 2 was double-blinded, placebo controlled, and investigated two…

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Issue #3 2016 – Digital edition

30 June 2016 | By European Pharmaceutical Review

In this issue: Biosimilars, Regulation, Packaging, Microfluidics, Microbiology, PAT, Antibiotic Resistance, and much more...

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Pneumococcal vaccine PnuBioVax safe and immunogenic in Phase I study

30 June 2016 | By Victoria White, Digital Content Producer

ImmBio has reported positive results from the First-in-Human study of its novel vaccine, PnuBioVax, against the bacterial pathogen Streptococcus pneumoniae...

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Antibiotics resistance Q&A

30 June 2016 | By Caroline Richards (European Pharmaceutical Review)

With the rise in drug-resistant bacterial infections heralding a new, dark era of medicine, antibiotics alternatives could one day become the first-line defence against infectious diseases. With the urgent need to find new approaches clear, Caroline Richards, Editor of European Pharmaceutical Review, interviewed Dr. Bjorn Herpers, Chief Medical Advisor of…

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AstraZeneca’s new antibiotic Zavicefta approved in the EU

28 June 2016 | By Victoria White, Digital Content Producer

The EC has granted marketing authorisation for Zavicefta for the treatment of patients with serious Gram-negative bacterial infections...

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Phase II study of relebactam in UTIs meets primary endpoint

21 June 2016 | By Victoria White, Digital Content Producer

The addition of relebactam is designed to restore activity of imipenem against certain imipenem-resistant strains of Gram-negative bacteria...

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Allecra Therapeutics closes €22 Million Series B financing round

15 June 2016 | By Victoria White, Digital Content Producer

The proceeds will fund Phase II development of AAI202 - a novel antibiotic combination designed to treat drug-resistant Gram-negative bacterial infections...

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Helperby’s new approach to fighting resistant bacteria

23 May 2016 | By Victoria White, Digital Content Producer

Helperby is about to begin clinical studies of a completely new approach to fighting resistant bacteria following a positive meeting with the FDA...

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Soligenix on IDR technology and SGX942

10 May 2016 | By Victoria White, Digital Content Producer

We discuss Innate Defense Regulator (IDR) technology with Soligenix's Chief Scientific Officer, Dr Oreola Donini, and find out more about SGX942...

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MGB Biopharma and FDA discuss MGB-BP-3 regulatory strategy

9 May 2016 | By Victoria White, Digital Content Producer

MGB Biopharma presented Phase I and preclinical data together with a proposal for the further development of oral MGB-BP-3 in C. difficile infections...

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Single Use: In-Depth Focus 2016

4 May 2016 | By European Pharmaceutical Review

In this Single Use In-Depth Focus: Disposables for continuous viral clearance for the production of monoclonal antibodies; Managing the quality of biologics manufactured by single use systems: A Japanese perspective; Single Use Q&A...

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The threat of antibiotic resistance

27 April 2016 | By Victoria White, Digital Content Producer

We've created an infographic on the threat of antibiotic resistance, highlighting some of the recommendations made by the Review on AMR...

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An international commitment to fighting antimicrobial resistance

11 April 2016 | By Victoria White, Digital Content Producer

Medical professionals, businesses and government officials from around the world have declared their commitment to fight antimicrobial resistance at ECCMID...

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Incentives and collaborations required to tackle superbugs, says GlobalData

2 February 2016 | By GlobalData

A GlobalData analyst says increased collaboration and further financial incentives are required to fight the mounting threat posed by superbugs...

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Allergan and AstraZeneca team up to develop ATM-AVI

29 January 2016 | By Victoria White

Allergan and AstraZeneca are to develop and commercialise ATM-AVI, an investigational, fixed-dose antibiotic combining aztreonam and avibactam...

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Antibiotics