news
Robotic method isolates high-producing cell lines for HIV vaccine production
Technical advances in vaccine production should shorten the time to clinical trials, breaking the logjam of promising new candidate vaccines waiting to be tested...
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Proteins
whitepaper
Application Note: Raman-based nutrient control in bioprocessing optimizes viable cell density and protein glycation
Production of protein therapeutics by mammalian cells is the most widely used bioprocess because of its ability to properly produce and fold a recombinant protein...
whitepaper
Whitepaper: pAVEwayTM – microbial expression system for the efficient large scale production of therapeutic proteins
pAVEway™ is an innovative expression system in E. coli that enables rapid creation of novel recombinant strains and the development of downstream processes that ensure industry leading product titres and efficient scale-up of the production of proteins of therapeutic utility...
whitepaper
Whitepaper: Downstream biopharmaceutical operations
The work presented here investigates the development and application of new bioprocess analytics in accordance with the aims of QbD...
news
Blood-based epigenetic may hold clues to autism
Epigenetic data reveals immune-response pathways that may prove critical to understanding autism...
webinar
Application of HDX-MS for drug discovery and development
13 October 2017 | By Thermo Fisher Scientific
In this webinar, theory and practice of HDX-MS will be discussed in conjunction with the topics of pharmaceutical industry...
whitepaper
Whitepaper: Raman-Based Nutrient Control in Bioprocessing Optimises Viable Cell Density and Protein Glycation
Production of protein therapeutics by mammalian cells is the most widely used bioprocess because of its ability to properly produce and fold a recombinant protein...
whitepaper
Poster: Accelerate antibody drug development with subdomain-specific affinity ligands
Scientists from Thermo Fisher Scientific discuss how the CaptureSelect affinity purification products and analytical tools have been developed for the discovery and manufacturing of therapeutic antibodies, including novel formats such as bi-specific antibodies and Fc-fusion proteins...
article
Subvisible particle identification in protein-based formulations by Raman spectroscopy
Subvisible particles in protein-based formulations can have different origins. Particles can be extrinsic (unexpected foreign material), intrinsic (from the production environment or primary packaging), and inherent (from the formulation). It is important that inherent particles (protein agglomerates) are distinguished from the other two types and that the extrinsic and intrinsic…
news
Inducing protein aggregation by extensional flow makes drugs less effective
9 May 2017 | By University of Leeds
Data from a new device demonstrates maximal levels of extensional flow which manufacturers could use for different processes, without damaging proteins...
article
Mass spectrometry in the development of protein biologics
Biological products, usually referred to as biologics, constitute a significant segment of pharmaceuticals in development. Biologics include therapeutic proteins, antibody drugs, antibody-drug conjugates (ADCs), vaccines, carbohydrates drugs, blood and tissue-derived pharmaceuticals, gene therapies, even live cells and tissues...
news
Stay ahead in Biopharma
The Thermo Fisher Scientific™ global bio/pharma tour is an opportunity to collaborate and network directly with experts in technology innovation...
news
Automating the development of aptamer-based biological tools with Tecan
24 February 2016 | By Tecan
The ARNA Laboratory in Bordeaux, France, is using DNA and RNA aptamers to develop novel tools for biological applications...
news
New UV-Vis Spectrophotometer simplifies sample quality decisions
Life scientists who work with DNA, RNA and proteins can make educated decisions about sample suitability in experiments using a standalone, microvolume spectrophotometer for accurate quantitation and purity measurements to ensure downstream application success.
news
Record attendance for Cambridge Healthtech Institute’s Seventh Annual PEGS Europe Summit
16 October 2015 | By CHI
Largest European Event for Biologics Returns to Lisbon from 2-6 November...
