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HIV (Human Immunodeficiency Virus)

NHS England to fund HIV treatment Rezolsta (darunavir/cobicistat)

30 March 2016 | By Victoria White

Darunavir/cobicistat is indicated for use in combination with other antiretroviral medications, for treating adults with HIV-1...

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Janssen announces results from its ongoing LATTE-2 study

26 February 2016 | By Victoria White

The LATTE-2 study showed that a regimen of two investigational long-acting, intramuscular (IM) formulations of HIV medicines had comparable antiviral activity to 3-drug oral antiretroviral therapy in HIV-1 infected adults...

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CHMP adopts positive opinion of Gilead’s Descovy

26 February 2016 | By Victoria White

Descovy is an investigational fixed-dose combination for the treatment of HIV-1 infection in adults and adolescents in combination with other HIV antiretroviral agents...

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Gilead announces results from study evaluating switching to F/TAF-based regimens from Truvada

24 February 2016 | By Victoria White

At Week 48 of the study, the F/TAF-based regimens were found to be statistically non-inferior to the F/TDF-based regimens in HIV-1 infected adult patients...

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Once-daily Isentress formulation meets endpoints in Phase III trial

23 February 2016 | By Victoria White

ONCEMRK is evaluating an investigational once-daily formulation of Isentress (raltegravir), known as raltegravir 600 mg, for previously untreated HIV-1 infected adults...

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EMA validates Gilead’s Type II variation application for Truvada for PrEP

1 February 2016 | By Victoria White

The application is based on the results of two large placebo-controlled trials of Truvada for PrEP, the Pre-Exposure Prophylaxis Initiative (iPrEX) and Partners PrEP...

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ViiV and Janssen progress two drug injectable HIV-1 treatment

8 January 2016 | By Victoria White

ViiV Healthcare has formalised its collaboration with Janssen for the Phase III investigation and commercialisation of the injectable formulations of cabotegravir and rilpivirine...

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BMS divests its HIV R&D assets to ViiV Healthcare

18 December 2015 | By Victoria White

ViiV will pay to Bristol-Myers Squibb upfront payments totaling $350 million with potential development and regulatory milestone payments of up to $518 million for the clinical assets and up to $587 million for the discovery and preclinical programmes...

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J&J announces new global commitments to end HIV infection in girls and women

2 December 2015 | By Victoria White

Johnson & Johnson has announced four new public-private partnerships to significantly reduce the burden of HIV incidence, especially among adolescent girls...

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EC grants marketing authorisation to Genvoya for HIV-1 infection

23 November 2015 | By

Genvoya is the first TAF-based regimen to receive marketing authorisation in the EU...

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FDA approves Gilead’s Genvoya for the treatment of HIV

6 November 2015 | By Victoria White

Genvoya contains a new form of tenofovir that has not been previously approved...

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Results announced for two drug injectable regimen for HIV maintenance therapy

3 November 2015 | By Victoria White

Results from the study show that cabotegravir and rilpivirine were comparable in maintaining viral suppression rates to a three drug oral regimen...

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CHMP adopts positive opinion of Edurant in adolescents with HIV-1

26 October 2015 | By Victoria White

If approved by the European Commission, Edurant will become available for the treatment of adolescents with HIV-1 for the first time...

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Bristol-Myers Squibb’s BMS-955176 completes proof-of-concept study

23 October 2015 | By Victoria White

BMS-955176 is a second-generation maturation inhibitor designed to inhibit one of the last steps of the HIV-1 viral lifecycle...

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Gilead announces Phase 3 results for investigational HIV treatment Genvoya

22 October 2015 | By Victoria White

Genvoya was found to be statistically non-inferior to Stribild based on percentages of patients with HIV-1 RNA levels less than 50 copies/mL...

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HIV (Human Immunodeficiency Virus)