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FDA grants Fast Track Designation to Novavax COVID-19 vaccine candidate
The FDA has given Fast Track Designation to NVX-CoV2373, Novavax’s COVID-19 vaccine candidate, created using recombinant nanoparticle technology.
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Nano-medicine
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Nanoformed formulation of piroxicam to enter Phase I trials
The first-in-human clinical trial of nanoformed piroxicam will begin in late 2020, with results expected by mid-2021.
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Team enhances bioavailability of simvastatin with mucoadhesive buccal films
Researchers have shown that mucoadhesive buccal films containing simvastatin inclusion complex and drug mixed micelles can improve the drug's bioavailability.
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Smart biomaterial drug delivery system could improve CNS injury recovery
The implanted biomaterial drug delivery system releases methylprednisolone and reduces inflammation, promoting central nervous system (CNS) repair.
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Nanoparticle delivery offers a possible alternative to opioid pain relief
An international team of researchers has used nanoparticles to deliver a drug – one that previously failed in clinical trials for pain – into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats. Nikki Withers spoke to Nigel Bunnett to hear more about…
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Modified liposome nanoparticles could be form of drug delivery, say researchers
By attaching cyclic peptides to modified liposomes, researchers have created a potential form of drug delivery able to cross the blood-brain barrier.
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75 percent of nanopharmaceuticals are being developed for oncology
A report states that three quarters of the roughly 230 nanopharmaceuticals in clinical development are for use as targeted cancer therapeutics.
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Spiral vortex streamlines delivery of nanomaterials into cells
Researchers have developed a new device, called a ‘spiral hydroporator’, which uses the power of a tiny fluid vortex to rapidly and efficiently deliver nanomaterials into cells.
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New adaptable material could be used as novel form of drug delivery
Researchers have developed a new rubber-like material that they say has the potential to be used as a form of drug delivery due to its nanopores.
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Nanocarrier could revolutionise chemotherapy drug delivery
Scientists have developed an innovative nanocarrier that can selectively target and deliver a chemotherapy payload to cancer cells without adverse effects on healthy cells.
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Supersensitive smart material developed for targeted drug delivery
Scientists have developed a highly sensitive material that can analyse multiple environmental parameters simultaneously, which could be used in drug delivery.
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Formulation, Development & Delivery In-Depth Focus 2019
Included in this in-depth focus are features on recombinant albumin as a versatile stabiliser and how nanobots will evolve as an effective drug delivery technique.
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Hitting the target – refining anticancer nanomedicine development
Mahfoozur Rahman and Sarwar Beg explain why we need to change tack from traditional formulation-driven development to a target-based approach in order to increase success with anticancer nanomedicine in the clinic.
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Nanoparticles useful in treating venomous snakebites
In the future, venomous snakebites could be treated using nanoparticles to bind the venom toxins and prevent them from spreading around the body...
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NIAID plan for in-depth tuberculosis research
NIAID has released a plan for research in the infectious disease TB in order to strengthen efforts and resolve to attack this disease...
