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Anti-Cancer Therapeutics

Novartis submit BLA for tislelizumab for oesophageal cancer treatment

15 September 2021 | By Anna Begley (European Pharmaceutical Review)

US FDA have accepted Biologics License Application (BLA) for tislelizumab for the treatment of oesophageal squamous cell carcinoma cancer.

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Neoadjuvant atezolizumab combination meets safety criteria in pleural mesothelioma

13 September 2021 | By Anna Begley (European Pharmaceutical Review)

Neoadjuvant cisplatin and pemetrexed in combination with atezolizumab met safety criteria in resectable pleural mesothelioma clinical study.

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Erleada^® reduces prostate-specific antigen (PSA) by 86 percent

13 September 2021 | By Anna Begley (European Pharmaceutical Review)

Erleada achieved an 86 percent reduction in PSA at 12 months in the majority of patients, shows post-hoc analysis of Phase III study.

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Melflufen increases refractory multiple myeloma survival in Phase III study

13 September 2021 | By Anna Begley (European Pharmaceutical Review)

Melfufen met the primary endpoint of superior progression free survival (PFS) with a median of 6.8 months in Phase III OCEAN trial.

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Imfinzi^™ and tremelimumab combo improves NSCLC outcomes

10 September 2021 | By Anna Begley (European Pharmaceutical Review)

Imfinizi™ and tremelimumab in combination with chemotherapy improved non-small lung cancer (NSCLC) survival by 23 percent in a Phase III study.

Pleural fluid cytology of lung (pulmonary) papillary adenocarcinoma

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Lumakras^™ (sotorasib) helps control brain metastases

10 September 2021 | By Anna Begley (European Pharmaceutical Review)

Amgen’s Lumakras™, a KRAS inhibitor, was found to improve the stability of brain metastases in a Phase II study.

Photomicrograph of diffuse B-cell lymphoma

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Minjuvi^® receives EC approval to treat large B-cell lymphoma

27 August 2021 | By Anna Begley (European Pharmaceutical Review)

European Commission (EC) approves Minjuvi with lenalidomide for the treatment of large B-cell lymphoma in adults.

Business people shaking hands behind technology images

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Pfizer to acquire Trillium immuno-oncology therapeutics

24 August 2021 | By Anna Begley (European Pharmaceutical Review)

Pfizer will acquire Trillium Therapeutics, an immuno-oncology company, potentially enhancing growth of cancer treatments from 2026.

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Abecma is the first treatment approved by EC for multiple myeloma

20 August 2021 | By Anna Begley (European Pharmaceutical Review)

The European Commission (EC) has approved Abecma, the first anti-BCMA CAR T-cell therapy for patients with multiple myeloma.

Endometrial adenocarcinoma under the microscope

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FDA approve GSK’s Jemperli for patients with dMMR solid tumours

18 August 2021 | By Anna Begley (European Pharmaceutical Review)

GSK receives FDA accelerated approval for Jemperli for adults with mismatch repair-deficient (dMMR) recurrent or advanced solid tumours.

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New NICE draft guidance recommends abemaciclib for breast cancer

13 August 2021 | By Anna Begley (European Pharmaceutical Review)

NICE has published draft guidance recommending Eli Lilly's twice-daily pill abemaciclib for advanced HER2-negative breast cancer.

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Enhertu improves survival in Phase III breast cancer trial

10 August 2021 | By Anna Begley (European Pharmaceutical Review)

Enhertu (trastuzumab deruxtecan) significantly improved survival in the DESTINY-Breast03 Phase III head-to-head trial against trastuzumab emtansine.

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Polivy^® with R-CHP significantly improves lymphoma outcomes

9 August 2021 | By Anna Begley (European Pharmaceutical Review)

Polivy

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Libtayo^® with chemotherapy trial stopped early due to success

6 August 2021 | By Anna Begley (European Pharmaceutical Review)

Phase III trial of Libtayo® (cemiplimab) combined with chemotherapy stops early due to significant improvement in overall survival in lung cancer patients.

Microscopic view of basal cell carcinoma

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Remetinostat shows promise as a BCC treatment in Phase II study

6 August 2021 | By Anna Begley (European Pharmaceutical Review)

Remetinostat, a first-in-class histone deacetylase inhibitor gel, displayed signs of clinical efficacy in patients with basal cell carcinoma.

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Anti-Cancer Therapeutics